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Official: Chinese vaccines’ effectiveness low

Official: Chinese vaccines’ effectiveness low
By JOE McDONALD and HUIZHONG WU18 minutes ago



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Gao Fu, director of the China Centers for Disease Control, speaks at the National Vaccines and Health conference in Chengdu in southwest China's Sichuan province Saturday, April 10, 2021. In a rare admission of the weakness of Chinese coronavirus vaccines, Gao the country's top disease control official says their effectiveness is low and the government is considering mixing them to give them a boost. (Chinatopix Via AP)


BEIJING (AP) — In a rare admission of the weakness of Chinese coronavirus vaccines, the country’s top disease control official says their effectiveness is low and the government is considering mixing them to get a boost.
Chinese vaccines “don’t have very high protection rates,” said the director of the China Centers for Disease Control, Gao Fu, at a conference Saturday in the southwestern city of Chengdu.
Beijing has distributed hundreds of millions of doses abroad while trying to promote doubt about the effectiveness of the Pfizer-BioNTech vaccine made using the previously experimental messenger RNA, or mRNA, process.
“It’s now under formal consideration whether we should use different vaccines from different technical lines for the immunization process,” Gao said.

Officials at a news conference Sunday didn’t respond directly to questions about Gao’s comment or possible changes in official plans. But another CDC official said developers are working on mRNA-based vaccines.

“The mRNA vaccines developed in our country have also entered the clinical trial stage,” said the official, Wang Huaqing. He gave no timeline for possible use.

Experts say mixing vaccines, or sequential immunization, might boost effectiveness. Researchers in Britain are studying a possible combination of Pfizer-BioNTech and the traditional AstraZeneca vaccine.

The coronavirus pandemic, which began in central China in late 2019, marks the first time the Chinese drug industry has played a role in responding to a global health emergency.

Vaccines made by two state-owned drug makers, Sinovac and Sinopharm, have been exported to 22 countries including Mexico, Turkey, Indonesia, Hungary, Brazil and Turkey, according to the foreign ministry.

The effectiveness of a Sinovac vaccine at preventing symptomatic infections was found to be as low as 50.4% by researchers in Brazil, near the 50% threshold at which health experts say a vaccine is useful. By comparison, the Pfizer-BioNTech vaccine has been found to be 97% effective.

Health experts say Chinese vaccines are unlikely to be sold to the United States, Western Europe and Japan due to the complexity of the approval process.

A Sinovac spokesman, Liu Peicheng, acknowledged varying levels of effectiveness have been found but said that can be due to the age of people in a study, the strain of virus and other factors.

Beijing has yet to approve any foreign vaccines for use in China.

Gao gave no details of possible changes in strategy but cited mRNA as a possibility.

“Everyone should consider the benefits mRNA vaccines can bring for humanity,” Gao said. “We must follow it carefully and not ignore it just because we have several types of vaccines already.”

Gao previously questioned the safety of mRNA vaccines. He was quoted by the official Xinhua News Agency as saying in December he couldn’t rule out negative side effects because they were being used for the first time on healthy people.

Chinese state media and popular health and science blogs also have questioned the safety and effectiveness of the Pfizer-BioNTech vaccine.

As of April 2, some 34 million people in China have received both of the two doses required for Chinese vaccines and about 65 million received one, according to Gao.

The Sinovac spokesman, Liu, said studies find protection “may be better” if time between vaccinations is longer than the current 14 days but gave no indication that might be made standard practice.


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Never knew vaccines could be mixed as well
It is like seals in the zoo getting a new ball. His word for "low" shouldn't be taken out of the context. What he meant was that it is "lower" than mRNA vaccines, not that is ineffective.
 
Lol. The Chinese vaccines contain the Covid virus. Who would be stupid enough to inject themselves with a "inactivated" Covid virus?

What if you make a mistake and some of the virus is still active?


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Read the statement from Chinese CDC published earlier today. The immunity generated by inactivated virus does not last long. In the UAE, many are receiving a third dose in as many months. The difference between mRNA and vector vaccine is the vehicle used to deliver the payload into the human cell - mRNA uses lipid nano particles and AstraZeneca uses chimp virus ChAdOx1.

Lipid nano particles are more effective at penetration while a vector virus is less effective and in addition the body develops immunity to the vector virus and destroys the vehicle before it has had a chance to deliver its payload.

The second difference, mRNA store the instructions in single-stranded RNA, the Oxford vaccine uses double-stranded DNA. mRNA is instructions (code) while Astrazeneca is actual DNA. .
Kudos to Turkish lady!!! Özlem Türeci for leading the mRNA work!.


 
Dude, I live in UK where the vaccine was developed and has been injected into more than 20 million people and so know how effective it is against hospitalisation with a single dose - 94%.

There is nothing you can teach me and so please do as I say before posting further.

You know statistics on millions of people through anecdotal experience?
 
frankly, being the husband of a front line Healthcare employee and based on the current stats, I think this virus and its various mutations are proving to be smarter than we initially thought...looks like even pfizer & moderna vaccines aren't having much of effect on it... hospital beds in the u.s. are filling up with serious coronavirus infections again...

 
No point fighting here. The Chinese bots here have a job to do , dont waste time on them.
Unfortunately the 2nd and 3rd waves in most countries is proving to be even more disastrous. In a few months winters will again come and then the effectiveness of the various vaccines will be quite clear.
Most vaccines are thought to have maximum effectiveness after 3 months of the 2nd dose. While some vaccines will require additional booster shots.
In the next few months a large part of the worlds population will be vaccinated. If the vaccines dont work , expect the virus to create even more havoc, as the danger of vaccine resistance might build up in our bodies. Newer vaccines might prove to be even lesser effective.
 
I think he is being taken out of context. He was trying to explain that mRNA vaccines are more effective than retroviral vaccines. mRNA vaccines produce a broad spectrum response making it a better option against new variants. This doesnt mean that vaccines like Sputnik, SinoPharm or Astera Zenca are any less effective. Mederna, Pifzer, Jhonson and Cansinobio should be prefered if available otherwise something is better than nothing.


I am going back to Australia soon so i hope govt over there dont force me to take Astrazenca. I would rather wait for pifzer or something that doesnt kill you by clotting.

it’s not taken out of context. It was discussed and revealed that mRNA vaccines would be more effective in the 1st place when we started developing vaccine, but China and Russia stuck to the traditional ones maybe they did not have the technology to build

and MRNA does not give broad spectrum protection. Messenger-RNA codes for a the specific protein for e.g a spike protein with that specific structure . So if a variant has a slightly different protein structure than the antibodies created by the M-RNA vaccine would not bind to the variant spike protein
 
The most important specification quality is the prevention of severe disease which some reports call as prevent hospitalization and death. This is over 90% for all vaccines past all trials I believe including the Chinese ones. The mild case type is described in very different ways and each vaccine trial staging by the producer is called and measured slightly differently.

The mild case or symptomatic prevention statistic is both quite useless because of the difference in how the different types are measured and also because it's not easy to measure it since everyone reacts differently. This is why even pfizor and AZ had some variance more than 10% in different countries.

However it is important that the prevent severe symptom to hospitalization and death statistic is compared because this is easier to accurately measure and also more meaningful measure.

Some people already won't show any symptoms even without vaccine. The mild case they call or prevention of any symptoms is difficult statistic to compare because each producer has different measure and trials in different countries return different results sometimes with difference up to 20%.

Pfizor one is best along with AZ I think for severe to death measurement but all the others are above 90% I believe. Long time since checking.

They are saying China also needs to quickly develop mRNA technology because not only good for developing vaccines but highly useful for many health science research. mRNA method to develop vaccine is extremely new and during the first rush, all China's state efforts were spent on adenovirus vaccine. mRNA would take much more time to develop because China has no basis in this technology then so risking the time is not wise. Now it is okay to take time and catch up in this area especially when the proof from time now shows it is a better vaccine and it is very useful technology for things like cancer research. Something all humans will benefit from whoever can develop it first just like nuclear fusion. Don't care if it's India, China, USA, or Ethiopia, it will benefit all humans if it is done. mRNA technology can help not just cancer fighting research but many other things too.
mRNA is less practically even in USA
Forget about china and its allies
Where is the cold chain equipment?
 
frankly, being the husband of a front line Healthcare employee and based on the current stats, I think this virus and its various mutations are proving to be smarter than we initially thought...looks like even pfizer & moderna vaccines aren't having much of effect on it... hospital beds in the u.s. are filling up with serious coronavirus infections again...

Well their 'high' efficiency is only for normal covid 19 not the mutations off shot of it which USA is getting a lot
Lol. The Chinese vaccines contain the Covid virus. Who would be stupid enough to inject themselves with a "inactivated" Covid virus?

What if you make a mistake and some of the virus is still active?


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This chart is wrong on Sinovac also if you don't know vaccines are suppose to inject an inactive virus for more than 100 years already this means you have no clue what you are talking about.
 
Well their 'high' efficiency is only for normal covid 19 not the mutations off shot of it which USA is getting a lot
I would advice you to apply breaks to this argument. Establish your medical credentials otherwise.

Pfizer is among the best shots out there but it is the South African B.1.351 strain which is proving challenging to tackle.

This chart is wrong on Sinovac also if you don't know vaccines are suppose to inject an inactive virus for more than 100 years already this means you have no clue what you are talking about.
Not necessarily. Every virus is different and potential risks of Flu-shot-type-Formula would vary accordingly. There are things that you do not seem to be familiar with, and it would be for the best to leave this matter to the better judgement of medical sciences and specialists to figure out. A better and safer solution will speak for itself.
 
Official: Chinese vaccines’ effectiveness low
By JOE McDONALD and HUIZHONG WU18 minutes ago



1 of 5
Gao Fu, director of the China Centers for Disease Control, speaks at the National Vaccines and Health conference in Chengdu in southwest China's Sichuan province Saturday, April 10, 2021. In a rare admission of the weakness of Chinese coronavirus vaccines, Gao the country's top disease control official says their effectiveness is low and the government is considering mixing them to give them a boost. (Chinatopix Via AP)


BEIJING (AP) — In a rare admission of the weakness of Chinese coronavirus vaccines, the country’s top disease control official says their effectiveness is low and the government is considering mixing them to get a boost.
Chinese vaccines “don’t have very high protection rates,” said the director of the China Centers for Disease Control, Gao Fu, at a conference Saturday in the southwestern city of Chengdu.
Beijing has distributed hundreds of millions of doses abroad while trying to promote doubt about the effectiveness of the Pfizer-BioNTech vaccine made using the previously experimental messenger RNA, or mRNA, process.
“It’s now under formal consideration whether we should use different vaccines from different technical lines for the immunization process,” Gao said.

Officials at a news conference Sunday didn’t respond directly to questions about Gao’s comment or possible changes in official plans. But another CDC official said developers are working on mRNA-based vaccines.

“The mRNA vaccines developed in our country have also entered the clinical trial stage,” said the official, Wang Huaqing. He gave no timeline for possible use.

Experts say mixing vaccines, or sequential immunization, might boost effectiveness. Researchers in Britain are studying a possible combination of Pfizer-BioNTech and the traditional AstraZeneca vaccine.

The coronavirus pandemic, which began in central China in late 2019, marks the first time the Chinese drug industry has played a role in responding to a global health emergency.

Vaccines made by two state-owned drug makers, Sinovac and Sinopharm, have been exported to 22 countries including Mexico, Turkey, Indonesia, Hungary, Brazil and Turkey, according to the foreign ministry.

The effectiveness of a Sinovac vaccine at preventing symptomatic infections was found to be as low as 50.4% by researchers in Brazil, near the 50% threshold at which health experts say a vaccine is useful. By comparison, the Pfizer-BioNTech vaccine has been found to be 97% effective.

Health experts say Chinese vaccines are unlikely to be sold to the United States, Western Europe and Japan due to the complexity of the approval process.

A Sinovac spokesman, Liu Peicheng, acknowledged varying levels of effectiveness have been found but said that can be due to the age of people in a study, the strain of virus and other factors.

Beijing has yet to approve any foreign vaccines for use in China.

Gao gave no details of possible changes in strategy but cited mRNA as a possibility.

“Everyone should consider the benefits mRNA vaccines can bring for humanity,” Gao said. “We must follow it carefully and not ignore it just because we have several types of vaccines already.”

Gao previously questioned the safety of mRNA vaccines. He was quoted by the official Xinhua News Agency as saying in December he couldn’t rule out negative side effects because they were being used for the first time on healthy people.

Chinese state media and popular health and science blogs also have questioned the safety and effectiveness of the Pfizer-BioNTech vaccine.

As of April 2, some 34 million people in China have received both of the two doses required for Chinese vaccines and about 65 million received one, according to Gao.

The Sinovac spokesman, Liu, said studies find protection “may be better” if time between vaccinations is longer than the current 14 days but gave no indication that might be made standard practice.


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Never knew vaccines could be mixed as well

I am glad that the Mods have finally taken action against these serial Anti-Chinese Indians who post nothing but propaganda and non-sense on this forum.
 
I would advice you to apply breaks to this argument. Establish your medical credentials otherwise.

Pfizer is among the best shots out there but it is the South African B.1.351 strain which is proving challenging to tackle.


Not necessarily. Every virus is different and potential risks of Flu-shot-type-Formula would vary accordingly. There are things that you do not seem to be familiar with, and it would be for the best to leave this matter to the better judgement of medical sciences and specialists to figure out. A better and safer solution will speak for itself.

Thanks mate... we have had enough of vaccine overload - all passionate nationalists need to back off. We need to overcome this plague together.
 
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