Do you think the US is at the point where it would essentially break off all diplomatic ties with Pakistan and impose economic sanctions?
Most Americans and American apologists are claiming that the transit route through Pakistan is largely irrelevant for the US anyway, so why would the US use leverage such as economic sanctions to get the transit route opened?
IMO, if the US did decide to impose unilateral economic sanctions on Pakistan, it would be over something different, perhaps something related to the nuclear program, if the US claims of the Pakistani transit route closure being 'no big deal' are correct.