Disappointing Chinese Vaccine Results Pose Setback for Developing World

[Hamartia Antidote]

Disappointing Chinese Vaccine Results Pose Setback for Developing World (Published 2021)

Brazil says CoronaVac has an efficacy rate just over 50 percent, much lower than previously announced. More than 380 million doses have already been ordered.

www.nytimes.com

Brazil says CoronaVac has an efficacy rate just over 50 percent, much lower than previously announced. More than 380 million doses have already been ordered.


Scientists in Brazil have downgraded the efficacy of a Chinese coronavirus vaccine that they hailed as a major triumph last week, diminishing hopes for a shot that could be quickly produced and easily distributed to help the developing world.

Officials at the Butantan Institute in São Paulo said on Tuesday that a trial conducted in Brazil showed that the CoronaVac vaccine, manufactured by the Beijing-based company Sinovac, had an efficacy rate just over 50 percent. That rate, slightly above the benchmark that the World Health Organization has said would make a vaccine effective for general use, was far below the 78 percent level announced last week.

The implications could be significant for a vaccine that is crucial to China’s global health diplomacy. At least 10 countries have ordered more than 380 million doses of the Sinovac inoculation, CoronaVac, though regulatory agencies have yet to fully approve it.

A senior official in Hong Kong, a special administrative region of China that had already ordered CoronaVac, said on Wednesday that an advisory panel would strictly review the vaccine based on clinical trial data before it was rolled out there.

“Those countries that have ordered the Chinese-made vaccines are probably going to question the usefulness of these vaccines,” said Yanzhong Huang, a senior fellow for global health at the Council on Foreign Relations and an expert on health care in China.

“Countries with opposition parties might use this to challenge the decision made by the incumbent government, and that will likely have domestic political implications in these countries,” Mr. Huang said.

Sinovac did not respond to multiple requests for comment.

For months, Chinese officials had said that the vaccines made by Sinovac and Sinopharm, a state-owned vaccine maker, would be important tools for fighting the pandemic in poorer countries that do not have extensive health care infrastructures. Unlike the vaccines made by the American drugmakers Pfizer and Moderna, they do not need to be frozen.

The Oxford-AstraZeneca and Johnson & Johnson vaccines, which can be refrigerated and are more effective than their Chinese counterparts, could provide an alternative. But it is now unclear if the governments that have bought CoronaVac can scrap their deals and turn to others.

CoronaVac, unlike some of the other vaccines, relies on older technology that uses chemicals to weaken or kill the virus, which is then put into a vaccine to spark antibodies in the recipient. But the process of killing the virus can weaken a vaccine’s potency, resulting in an immune response that could be shorter or less effective.

The lower efficacy announced Tuesday would mean it would take longer for countries that use CoronaVac’s vaccine to reach “herd immunity,” the point at which enough people are resistant to the virus — roughly 70 percent, many scientists have said — that it is vanquished in a population. By contrast, the vaccines made by Moderna and Pfizer-BioNTech have been shown to have an efficacy rate of about 95 percent.

“This was one of the reasons the Americans and Europeans didn’t go with this older technology,” said John Moore, a vaccine expert at Cornell University. “A well-maintained Ford Model T would probably get you from Wuhan to Beijing, but personally I would prefer a Tesla.”

Brazil’s health regulatory agency, Anvisa, is reviewing data from the trial, which relied on volunteers who are health care professionals. If Anvisa approves emergency use of CoronaVac, officials hope to start giving out shots in Brazil late this month. It has roughly 10.8 million doses of CoronaVac on hand. Last week, Brazil’s health minister, Eduardo Pazuello, said the government intended to purchase 100 million doses of CoronaVac.

Natalia Pasternak, a microbiologist and the president of Instituto Questão de Ciência, a Brazilian nongovernmental organization, told reporters on Tuesday that the results of the trial meant it would not be a panacea.

“It is not the best vaccine in the world,” she said at the news conference during which the efficacy rate was disclosed. But she called it a “perfectly acceptable vaccine” that would lead to fewer patients developing serious cases or dying from the virus.

 

[Suriya]

When Modi said Indian made vaccines are going to savior he wasn't bluffing after all.

India's Serum institute which is already the biggest makes of vaccines is currently making Oxford-AstraZeneca vaccine and would be the most likely candidate for global supply.

While fully made in India Bharat biotec's covaxin which efficacy likely to be more than 60% would another better and safer alternative to most vaccines.

 

[313ghazi]

I've always thought we should have an international body working under something like WHO funding cost price medication and research around the world.

This is a global problem - why aren't we all working together.

 

[CAPRICORN-88]

That is because they discovered that Sinovac vaccines are administered to those who have already been tested positive or contacted COVID-19 in Brazil.
Brazil has just place and order for 100 million dose of Sinovac vaccines following that.
This has already been posted in another similar thread, why is it repeated again?

 

[hualushui]

If measured by the same standard, what is the effectiveness of Western vaccines such as Pfizer?
Why did Pfizer executives sell stocks?

 

[shi12jun]

https://www.bloomberg.com/news/arti...f-vaccination-risks-for-sick-patients-over-80

 

[denel]

I've always thought we should have an international body working under something like WHO funding cost price medication and research around the world.

This is a global problem - why aren't we all working together.

100% on the mark. We have a global non profit vaccine. This is a global problem and yet it is pathetic to see these CMPT psyops bots making mockery of deaths all over the world. We need to stop this bug on its heal.

I dont care who delivers it but if it works, we take it - end of story.

Just look at this thread; you will see the CMPT clowns all sowing disinformation and mud slinging; same people who gave this bs to entire planet fail to take any responsibility and then have to maoist balls (if he had any to begin with) to start going in various direction.

 

[52051]

Pfizer mRNA have cause so many death and they still remain silent, whilst Chinese vaccines have made over 14 million shot already world-wide, and the West biased joking media try their best to dig dirt and find nothing?

As for the so-called 50% efficency, guess what, do you even read the report?

The SinoVac's 50% is the protection rate that including health carriers, as for medium to server condition, the rate of protection is 100% according to Brazil.

Basically with SinoVac's vaccine, even if you expose at the virus, at worst you will get light condition and recovered soon after, like light cough etc, it wont develop into medium to critical condition.

By the same standard, which considered health carriers and with sufficient length of tracking, what is the protection rate of Pfizer mRNA death trap? According to the US Editor of the top medical Journal, the protection rate of Pfizer could be 19% instead of 95% they claimed.

And SinoVac's vaccines is so much safer than the mRNA death trap, no wonder in black market it cost 3 times higher than the US vaccines despite the retarded west media smear campaign.

 

[52051]

go drink something from your CMPT bot coolaid. No one is listening to your PLA troll bot factory kak.

My ignore list of CMPT insect is getting larger and larger.

Nobody gives a damn to you, who cares whatever vaccine you take, nothing changes that many have died by Pfizer's death trap, including the recent 23 from Norway.

If Pfizer's death trap were invented by China, just imagine the shitstorm the west media and their bots, as well as the idiots like you would have been bring on, hehehe

 

[GumNaam]

That is because they discovered that Sinovac vaccines are administered to those who have already been tested positive or contacted COVID-19 in Brazil.
Brazil has just place and order for 100 million dose of Sinovac vaccines following that.
This has already been posted in another similar thread, why is it repeated again?

now why the hell would give ANY vaccine to someone who is already sick?

even when you go to get the flu vaccine, they won't give it to you if you are already suffering from the flu! same principle applies here.

 

[Han Patriot]

now why the hell would give ANY vaccine to someone who is already sick?

even when you go to get the flu vaccine, they won't give it to you if you are already suffering from the flu! same principle applies here.

That's what the Brazilians did, they gave it to. Infected test subjects. Using our criteria, Pfitzer would only be 19% effective, but who cares, its Chinese so its bad, but 23++ ppl died alrwdy.

 

[FairAndUnbiased]

now why the hell would give ANY vaccine to someone who is already sick?

even when you go to get the flu vaccine, they won't give it to you if you are already suffering from the flu! same principle applies here.

because Bolsonaro is a crazy right wing racist that hates Chinese people. He's the Brazilian discount Trump.

 

[CAPRICORN-88]

now why the hell would give ANY vaccine to someone who is already sick?

even when you go to get the flu vaccine, they won't give it to you if you are already suffering from the flu! same principle applies here.

Simple. Some of these trial patient knowingly and unknowingly have already acquired Covid and may be hoping that the vaccine will cure them.
In 3rd world nation, contact tracing is almost none existent. India is a typical example with some industrial nations also in the list. They won't even wear masks.
1.The actual testing involved 4 group with China Sinovac vaccines in the 3rd stage trials administering to the most vulnerable group as per WHO procedure while Pfizer & Modena vaccine generally tested on easier 1st and 2nd group that are generally younger and healthier.
2. Real Sinovac vaccine were administered to only 50% of the trial patient while thr other 50% gets placebo jabs.

That is why Brazil placed an order for 100 million dose of China vaccines. Thr Brazil President is well known to be anti-China Trump supporters and is pushing US Pfizer vaccines against his Health Experts advice.

 

[FuturePAF]

I've always thought we should have an international body working under something like WHO funding cost price medication and research around the world.

This is a global problem - why aren't we all working together.

Unfortunately due to international politics, and point scoring between nations; never letting a crisis go to waste, and COVID is a doosey of an international crisis (along with the economic effects)

 

[drumstick]

because Bolsonaro is a crazy right wing racist that hates Chinese people. He's the Brazilian discount Trump.

chinese here call new strain British virus but others are racist and not chinese.... everyone is now aware of how chinese vaccine failed... and Brazil showed the world that sinovac efficacy is at 50.4% which is really really bad.