I think it's also safe to say the map of the middle East will not stay the way it is now. Very high probability that the Kurd's will get an official, internationally recognized state of their own in the next 10 years comprising former parts of Syria and Iraq, maybe even a little bit of Turkey. Assad will support this, it's less territory for him to control and he needs all the friends he can get, so if a Kurdish state is holding his enemies in check, then that's a bonus for him.
Moderate Sunni's might be brought to the table and given a country of their own as well. Including parts of IRaq and Syria, this " Sunnistan" could put and end to the ISIL recruitment if more moderate factions are seen as accomplishing this goal by the general Sunni population.
Less likely but possible, Palestine is another country that could see itself recognized as an independent state.
This of course is all bad for Israel and the US. The US Military Industrial complex makes Billions of dollars from death and destruction all over the planet and their ability to influence foreign governments comes from the threat of insurrection and civil war against any government that doesn't follow orders. Israel needs more land to accommodate all the Jews that are "coming home" to Israel from other parts of the world. Their ability to grab land is based on war, every time there's a war with Gaza they grab a another chunk of land for settlement expansion. Also, as the primary recipient of US military support, their economy is tied to the US military Industrial complex as well.
So these 2 parties have no interest in peace, it's up the European's and Asians to expand their influence in this part of the world and try to push positive and peaceful change, if that's even possible.