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Genetic Map of Pakistan

Here's all the sources

~ Sources ~
-Kalash Genetic Isolate: Ancient Divergence, Drift, & Selection by Q. Ayub (2015)

-mtDNA sequence diversity of Hazara ethnic group from Pakistan by A. Rakha (2017)

-An Ethnolinguistic and Genetic Perspective on the Origins of the Dravidian-Speaking Brahui in Pakistan by L. Pagani (2017)

-Separating the post-Glacial coancestry of European and Asian Y chromosomes within haplogroup R1a by P.A. Underhill (2010)

-Y-Chromosomal DNA Variation in Pakistan by R. Qamar; Q. Ayub; A. Mohyuddin (2002)

-Whole genome sequencing of an ethnic Pathan (Pakhtun) from the north-west of Pakistan by M. Ilyas (2015)

-Genetic analysis of mitochondrial DNA control region variations in four tribes of Khyber Pakhtunkhwa, Pakistan by S. Bhatti (2016)

-Genetic characterization of the Makrani people of Pakistan from mitochondrial DNA control-region data by M.H. Siddiqui (2015)

-Mitochondrial DNA variation in the Sindh population of Pakistan by S. Bhatti (2015)

-Genetic perspective of uniparental mitochondrial DNA landscape on the Punjabi population, Pakistan by S. Bhatti (2017)

-“Like sugar in milk”: reconstructing the genetic history of the Parsi population by Gyaneshwer Chaubey

Care to tell me from which specific source does this diagram comes from?
29512568_1853395471387095_1667191826248892416_o.jpg


And specially this line

"The studies reveal that Pakistani share about 50% to 70% of their DNA with South Asian, about 20% to 40% with Eurasians and about 10% between East Asians and Sub-Saharans."

This runs contrary to the knowledge that ALL Humans share more than 95% of their genome --ie their complete DNA set, usually found in the nucleus of diploid somatic cells-- among each other.

Lastly, did you make this diagram yourself or are you referring/adapting it from somewhere?
 
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Care to tell me from which specific source does this diagram comes from?

And specially this line

"The studies reveal that Pakistani share about 50% to 70% of their DNA with South Asian, about 20% to 40% with Eurasians and about 10% between East Asians and Sub-Saharans."

This runs contrary to the knowledge that ALL Humans share more than 95% of their genome --ie their complete DNA set, usually found in the nucleus of diploid somatic cells-- among each other.

Lastly, did you make this diagram yourself or are you referring/adapting it from somewhere?

Gene clusters from Rosenberg (2006) for K=7 clusters. (Cluster analysis divides a dataset into any prespecified number of clusters.) Individuals have genes from multiple clusters. The cluster prevalent only among the Kalash people (yellow) only splits off at K=7 and greater.

https://en.wikipedia.org/wiki/Human_genetic_clustering#/media/File:Rosenberg2007.png



https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1244-9

https://media.springernature.com/fu...-9/MediaObjects/13059_2017_1244_Fig3_HTML.gif
 
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Gene clusters from Rosenberg (2006) for K=7 clusters. (Cluster analysis divides a dataset into any prespecified number of clusters.) Individuals have genes from multiple clusters. The cluster prevalent only among the Kalash people (yellow) only splits off at K=7 and greater.

https://en.wikipedia.org/wiki/Human_genetic_clustering#/media/File:Rosenberg2007.png



https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1244-9

https://media.springernature.com/full/springer-static/image/art:10.1186/s13059-017-1244-9/MediaObjects/13059_2017_1244_Fig3_HTML.gif

None of these sources state this.

"The studies reveal that Pakistani share about 50% to 70% of their DNA with South Asian, about 20% to 40% with Eurasians and about 10% between East Asians and Sub-Saharans."

Did you infer this or are you quoting some specific study?

BTW, from your very source this statement comes.

https://en.wikipedia.org/wiki/Human_genetic_clustering

There is broad scientific agreement that a relatively small fraction of human genetic variation occurs between populations, continents, or clusters.

I will not call a mere 10% sharing a "relatively small fraction of human genetic variation".

May be you are confusing DNA with something else.
 
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None of these sources state this.



Did you infer this or are you quoting some specific study?

It's based on the collection of data....have you ever heard of something called Genetic-distance and Cluster analysis? And the map was made by a member of anthrogenica.com and posted this map on reddit.

A genetic map of Pakistan

http://dienekes.blogspot.com/2011/01/genetic-map-of-pakistan.html

 
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Genetic-distance and Cluster analysis?
I am very well aware of edit-distances and how it is used to find genetic-drift or clustering and use of clustering algorithms.
What I find rather intruging is your statement from the figure. The reason is because it leads to some really interesting conclusions which likes of @Iqbal Ali draw.
https://defence.pk/pdf/threads/genetic-map-of-pakistan.558317/page-3#post-10606279

Science does not support a world view. It generates one.

It's based on the collection of data....have you ever heard of something called Genetic-distance and Cluster analysis? And the map was made by a member of anthrogenica.com and posted this map on reddit.

A genetic map of Pakistan

http://dienekes.blogspot.com/2011/01/genetic-map-of-pakistan.html

Good!
So it is an edited reditt/blog post.
Let me read it please.
 
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It's based on the collection of data....have you ever heard of something called Genetic-distance and Cluster analysis? And the map was made by a member of anthrogenica.com and posted this map on reddit.

A genetic map of Pakistan

http://dienekes.blogspot.com/2011/01/genetic-map-of-pakistan.html

Alright first thing first:-

The blog post you mentioned contains MDS (Multi-demensional Scaling) plots of genotype (meaning DNA) raw data of 9 population from Pakistan with 23-25 samples each -- probably collected using 23andMe.

To understand what this means you need to know what MDS plots are. MDS are essentially a non-linear dimensionality reduction technique. I am quite familiar with Dimensionality Reduction and use PCA quite often for my own work.

One easy to access source is this :-
https://ncss-wpengine.netdna-ssl.co.../Procedures/NCSS/Multidimensional_Scaling.pdf

"Multidimensional scaling (MDS) is a technique that creates a map displaying the relative positions of a number of objects, given only a table of the distances between them. "

This is a very important point. MDS takes as input the distances between the multi-dimensional data. Here that input is going to be Genetic Distance, which is an edit distance based on DNA substitution model. It then projects this information into a number of dimensions that you mention as input and you can use these plots to identify clusters.

It is noteworthy, that this information it works on is NOT the DNA itself but the genetic distance between DNA(s). This is the reason why any of the MDS plot itself can not give you answer to "how much DNA do these population share" BUT rather it tell you "how close do these data gather" also that is what you call a cluster. Obviously, you mis-understood clustering of genetic distance as absolute sharing of DNA and that gave you this weird idea that Pakistani only share 10% DNA with sub-saharans. And then likes of @Iqbal Ali found "affirmation" to their "commonly held Pakistani believes".

This is very text book example of how NOT to do science.
 
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Alright first thing first:-

The blog post you mentioned contains MDS (Multi-demensional Scaling) plots of genotype (meaning DNA) raw data of 9 population from Pakistan with 23-25 samples each -- probably collected using 23andMe.

To understand what this means you need to know what MDS plots are. MDS are essentially a non-linear dimensionality reduction technique. I am quite familiar with Dimensionality Reduction and use PCA quite often for my own work.

One easy to access source is this :-
https://ncss-wpengine.netdna-ssl.co.../Procedures/NCSS/Multidimensional_Scaling.pdf

"Multidimensional scaling (MDS) is a technique that creates a map displaying the relative positions of a number of objects, given only a table of the distances between them. "

This is a very important point. MDS takes as input the distances between the multi-dimensional data. Here that input is going to be Genetic Distance, which is an edit distance based on DNA substitution model. It then projects this information into a number of dimensions that you mention as input and you can use these plots to identify clusters.

It is noteworthy, that this information it works on is NOT the DNA itself but the genetic distance between DNA(s). This is the reason why any of the MDS plot itself can not give you answer to "how much DNA do these population share" BUT rather it tell you "how close do these data gather" also that is what you call a cluster. Obviously, you mis-understood clustering of genetic distance as absolute sharing of DNA and that gave you this weird idea that Pakistani only share 10% DNA with sub-saharans. And then likes of @Iqbal Ali found "affirmation" to their "commonly held Pakistani believes".

This is very text book example of how NOT to do science.


Ok bihari...anything else?

It's so funny watching these Gangetic monkeys getting triggered that they aren't Indo Aryans. Lmfao.

Dasyu trash.
 
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Alright first thing first:-

The blog post you mentioned contains MDS (Multi-demensional Scaling) plots of genotype (meaning DNA) raw data of 9 population from Pakistan with 23-25 samples each -- probably collected using 23andMe.

To understand what this means you need to know what MDS plots are. MDS are essentially a non-linear dimensionality reduction technique. I am quite familiar with Dimensionality Reduction and use PCA quite often for my own work.

One easy to access source is this :-
https://ncss-wpengine.netdna-ssl.co.../Procedures/NCSS/Multidimensional_Scaling.pdf

"Multidimensional scaling (MDS) is a technique that creates a map displaying the relative positions of a number of objects, given only a table of the distances between them. "

This is a very important point. MDS takes as input the distances between the multi-dimensional data. Here that input is going to be Genetic Distance, which is an edit distance based on DNA substitution model. It then projects this information into a number of dimensions that you mention as input and you can use these plots to identify clusters.

It is noteworthy, that this information it works on is NOT the DNA itself but the genetic distance between DNA(s). This is the reason why any of the MDS plot itself can not give you answer to "how much DNA do these population share" BUT rather it tell you "how close do these data gather" also that is what you call a cluster. Obviously, you mis-understood clustering of genetic distance as absolute sharing of DNA and that gave you this weird idea that Pakistani only share 10% DNA with sub-saharans. And then likes of @Iqbal Ali found "affirmation" to their "commonly held Pakistani believes".

This is very text book example of how NOT to do science.
Point is, we Pakistanis have nothing in common with Indians.

You can say whatever you like, but the fact remains that we Pakistanis are different from Indians.
 
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Ok bihari...anything else?

It's so funny watching these Gangetic monkeys getting triggered that they aren't Indo Aryans. Lmfao.

Dasyu trash.
Yeah Yeah, keep on calling all sorts of name, it shows who is triggered. :lol: :rofl: BTW, what do you know about genetic distances, lets hear it. Or about clustering? I guess nothing. A hack job of copy paste can get you only so far :rofl: :lol:

You come from the country where Water Fueled Cars are taken seriously so no wonder your knowledge of any discipline of science is broken.

Good luck Mr. Dumb-istani.

Point is, we Pakistanis have nothing in common with Indians.

You can say whatever you like, but the fact remains that we Pakistanis are different from Indians.
Keep on chanting it till death and it won't change a bit of reality. Pakistani have extreme similarity to north Indians and there is nothing you can do about it, even a single bit.
 
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Yeah Yeah, keep on calling all sorts of name, it shows who is triggered. :lol: :rofl: BTW, what do you know about genetic distances, lets hear it. Or about clustering? I guess nothing. A hack job of copy paste can get you only so far :rofl: :lol:

You come from the country where Water Fueled Cars are taken seriously so no wonder your knowledge of any discipline of science is broken.

Good luck Mr. Dumb-istani.


Keep on chanting it till death and it won't change a bit of reality. Pakistani have extreme similarity to north Indians and there is nothing you can do about it, even a single bit.
Just like French and Germans and Italians are similar....
 
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Keep on chanting it till death and it won't change a bit of reality. Pakistani have extreme similarity to north Indians and there is nothing you can do about it, even a single bit.
Their are indeed similarities in areas adjacent to the Radcliffe line ie you will find Bajwas, Randhawas,Gills etc on both sides but heck no their is no "extreme similarity" between Pakistanis and the descendants of the naked, primitive, feral, banana eating, tarantula munching savages of the ancient Ganga forests (Your ancestors):agree::agree::agree::agree:.Now log off and take you propaganda elsewhere as your superiors from the historical Indus could not give two hoots.
 
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29433215_1853395508053758_7059925069157367808_o.png

Photo: Consensus Neighbor-Joining Tree of Populations. The thickest edges have at least 95% bootstrap support, and the edges of intermediate thickness have at least 75% support. If all of the groups subtended by an edge have majority membership in the same cluster in Figure 2A (or only plurality membership in the cases of Hazara , Makrani, and Uygur), the edge is drawn in the same color as was used for the cluster.

North Indians like to claim they "Aryan". Unfortunately, genetics has proven them wrong. The only Indian population with a significant Eurasian component are the Parsis. This means that the Aryan migration occured only up to the Indus Valley and that Vedic clans mainly remained in the Indus, with only the Bharatas and a handful of others migrating to Ganga in 1200 BCE.
29497979_1853395591387083_6063915959872126976_n.jpg

Photo: Results of ADMIXTURE analysis (K8) of world populations with a zoom-in on Iranian, Parsis, Pakistanis and other South Asian populations.

29468923_1853395528053756_8702125940999716864_n.jpg

Photo: Human genetic variation with 15 inferred ancestral components for Pakistani groups (K15).
Mirpuri kuhdur gyah? :taz:
 
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Mirpuri are a linguistic group. Genetically they are similar to Northern Punjabis.
Do you have any evidence to back that up, I don't consider myself to be punjabi in anyway but have quite a few punjabi friends.
From face value the phenotypes exhibited seem rather varied even within the same ethnicity.
 
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