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Coronavirus Vaccine Update: China's Sinovac Biotech 90% Successful in Phase I and II Trials, Final T

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Coronavirus Vaccine Update: China's Sinovac Biotech 90% Successful in Phase I and II Trials, Final Tests in Brazil
World Team Latestly| Jun 14, 2020 03:24 PM IST

Beijing, June 14: Sinovac Biotech, the Chinese pharmaceutical firm which has emerged as the top candidate to develop a vaccine against coronavirus, claimed success in phase I and phase II of the human trials. The potential vaccine, which it has named as CoronaVac, was successful in inducing antibodies against the SARS-CoV-19 virus which causes the COVID-19 infection.

The vaccine maker, in a statement, said 90 percent of the people were administered with the vaccine developed antibodies which successfully resisted the COVID-19 infection. Not only was the vaccine found effective, no major side-effect was recorded on those who were part of the trials.

Sinovac would submit the findings of its trial to top medical journals for peer-based critical review. A total of 743 people, with no comorbidities, were selected for the trials. They were aged in the range of 18 to 59, the pharmaceutical firm said.

In phase 1 of the trials, they were provided shots of the vaccine at an interval of 14 days. In the second phase, they were administered vaccine shots at 28-day interval. With the trials being largely successful, the company is looking forwards towards the final round of tests that will be conducted in Brazil.

Sinovac has tied up with Instituto Butantan to conduct its phase III trial in Brazil. The latter has also inked an agreement with AstraZeneca - the UK-based drug-maker - which claims to be on track to manufacture the vaccine by September. AstraZeneca would also be conducting the final human trials in the Latin American nation.

https://www.latestly.com/world/coro...-ii-trials-final-tests-in-brazil-1821918.html
 
Coronavirus Vaccine Update: China's Sinovac Biotech 90% Successful in Phase I and II Trials, Final Tests in Brazil
World Team Latestly| Jun 14, 2020 03:24 PM IST

Beijing, June 14: Sinovac Biotech, the Chinese pharmaceutical firm which has emerged as the top candidate to develop a vaccine against coronavirus, claimed success in phase I and phase II of the human trials. The potential vaccine, which it has named as CoronaVac, was successful in inducing antibodies against the SARS-CoV-19 virus which causes the COVID-19 infection.

The vaccine maker, in a statement, said 90 percent of the people were administered with the vaccine developed antibodies which successfully resisted the COVID-19 infection. Not only was the vaccine found effective, no major side-effect was recorded on those who were part of the trials.

Sinovac would submit the findings of its trial to top medical journals for peer-based critical review. A total of 743 people, with no comorbidities, were selected for the trials. They were aged in the range of 18 to 59, the pharmaceutical firm said.

In phase 1 of the trials, they were provided shots of the vaccine at an interval of 14 days. In the second phase, they were administered vaccine shots at 28-day interval. With the trials being largely successful, the company is looking forwards towards the final round of tests that will be conducted in Brazil.

Sinovac has tied up with Instituto Butantan to conduct its phase III trial in Brazil. The latter has also inked an agreement with AstraZeneca - the UK-based drug-maker - which claims to be on track to manufacture the vaccine by September. AstraZeneca would also be conducting the final human trials in the Latin American nation.

https://www.latestly.com/world/coro...-ii-trials-final-tests-in-brazil-1821918.html
If it's that good then why are the trying to hack vaccine research of America and UK?
 
China holds the keys in production of virus vaccine
ST_20200528_XVACCINE_5696948.jpg

An engineer conducting tests on an experimental vaccine for the coronavirus at a biopharmaceutical company in Beijing last month.PHOTO: AGENCE FRANCE-PRESSE

PUBLISHED
MAY 28, 2020, 5:00 AM SGT

It is said to control 80% of global output of ingredients needed for generic medicines

Shannon Teoh Malaysia Bureau Chief In Kuala Lumpur

China's control of the base ingredients to make medicines gives the Asian giant leverage over the production of a coronavirus vaccine no matter who wins the global race to discover it.

A host of nations such as the United States, Britain, France and Australia - as well as Singapore and Malaysia - are desperately pursuing a vaccine for the Covid-19 disease, which has infected nearly six million people and killed more than 350,000 globally since it was discovered in the central Chinese city of Wuhan last December.

While there is no exact data on China's market share of the core components used in pharmaceuticals, New York-based bioethics research institute Hastings Centre's senior adviser Rosemary Gibson told The Straits Times that China controls about 80 per cent of global production of the raw materials and chemicals required to manufacture generic medicines.

This could give Beijing a crucial advantage even as tensions with Washington have intensified amid a blame game over the cause of the highly infectious disease that has put more than half of humanity into various levels of lockdown.

"That certainly gives you an advantage and a potential monopoly position over the manufacture of it," Ms Gibson said in an online briefing early yesterday by the Washington-based National Press Foundation (NPF).

She added that it was a huge problem for the US as, aside from a Covid-19 vaccine, the country "can't make antibiotics any more" for related respiratory illnesses like pneumonia and bronchitis.

We depend on China largely for those core chemicals, as does the world," she said.

On paper, China has only 13 per cent of global manufacturing facilities for active pharmaceutical ingredients (API), which is less than half of America's share.

But according to US Senate Finance Committee chairman Chuck Grassley last year, 80 per cent of APIs used in drugs consumed by Americans are imported, largely from China and India.

Further upstream, China also holds a near-monopoly on thousands of key starting materials, such as chemical intermediates and ingredients from antibiotic fermentation plants and pigs.


The Asian superpower's pharmaceutical industry has benefited in the past from cornering the supply chain by increasing manufacturing capacity and by what Ms Gibson said were cartel-like practices such as price fixing.

The US stopped making penicillin antibiotics in 2004, with China winning a price war that Ms Gibson said was aided by government subsidies. China dominated over two-thirds of penicillin production in 2006 before prices more than doubled in 2007.

India may appear a viable alternative supplier, but even its huge generic drugs industry relies on China for 69 per cent of its raw materials.

But concerns over Beijing holding the world to ransom could be tempered by the inter-dependence in trade for healthcare goods used in fighting the coronavirus.

Senior trade policy analyst Sebastien Miroudot of the Organisation for Economic Cooperation and Development (OECD) said that during the pandemic, there have not been shortages in pharmaceuticals similar to those seen in goods such as protective gear, test kits, disinfectants and ventilators.

OECD data shows that no country in 2018 had more than 15 per cent of the global share of exports of these items. Singapore was 13th and Malaysia 17th behind global leader Germany.

"Indeed, while the United States and Germany tend to specialise in the production of medical devices, China and Malaysia are most specialised in producing protective garments," it said in a May 5 report that showed that the US and China were in the world's top four for both imports and exports of medical equipment needed during the coronavirus pandemic.

Mr Miroudot added during the NPF briefing that "countries are specialised in specific types of Covid-19 goods and depend on each other".

"The top exporter of face masks is China, but if we look at intubation kits, the top exporter is the US. If we look at surgical gloves, it is Malaysia. It is really a world of trade inter-dependencies," he said.

https://www.straitstimes.com/asia/china-holds-the-keys-in-production-of-virus-vaccine

Coronavirus: China a winner no matter who comes first in global race for vaccine
5 HOURS AGO

ab_vaccine_270520.jpg


KUALA LUMPUR - China's control of the base ingredients to make medicines gives the Asian giant leverage over the production of a coronavirus vaccine no matter who wins the global race to discover it.

A host of nations such as the United States, United Kingdom, France and Australia - even Singapore and Malaysia are on the list - are desperately pursuing a vaccine to end the pandemic that has infected nearly six million and killed more than 350,000 since it was discovered in the central Chinese city of Wuhan in December.

While there is no exact data on China's market share of the core components used in pharmaceuticals, New York-based bioethics research institute Hastings Center's senior adviser Rosemary Gibson told The Straits Times that China controls about 80 per cent of global production of the raw materials and chemicals required to manufacture generic medicines.

This could give Beijing a crucial advantage even as tensions with Washington have intensified during the Covid-19 outbreak amid a blame game over the cause of the highly infectious disease that has put more than half of humanity into various levels of lockdown.

"That certainly gives you an advantage and potential monopoly position over the manufacture of it," Ms Gibson said in an online briefing early on Wednesday (May 27) on medical supply chains by the Washington-based National Press Foundation (NPF).

She added that it was a huge problem for the US as, aside from a Covid-19 vaccine, the US "can't make antibiotics any more" for related respiratory illnesses like pneumonia and bronchitis.

"We depend on China largely for those core chemicals as does the world," she said.

On paper, China has only 13 per cent of global manufacturing facilities of active pharmaceutical ingredients (API) that are mixed to create a finished drug. While this is less than half of the US' share, its Senate Finance Committee chairman Chuck Grassley wrote last year that 80 per cent of APIs used in drugs consumed by Americans are imported, largely from China and India.

China also holds a near-monopoly further upstream on thousands of key starting materials such as chemical intermediates and ingredients from antibiotic fermentation plants and pigs. The Asian superpower's pharmaceutical industry has benefited in the past from cornering the supply chain by increasing manufacturing capacity and what Ms Gibson said were cartel-like practices such as price-fixing.

The US stopped making penicillin antibiotics in 2004, with China winning a price war that Ms Gibson said was aided by government subsidies. China dominated over two-thirds of penicillin production in 2006 before prices more than doubled in 2007.

India may appear a viable alternative supplier, but even its huge generic drugs industry relies on China for 69 per cent of its raw materials.

However, concerns over Beijing holding the world to ransom could be tempered by the interdependence on trade for healthcare goods used in fighting the coronavirus.

Senior trade policy analyst Sébastien Miroudot of the Organisation for Economic Cooperation and Development (OECD) said that, during the pandemic, there have not been similar shortages in pharmaceuticals as seen in goods such as protective gear, test kits, disinfectants and ventilators.

OECD data shows that no country in 2018 had more than 15 per cent of the global share of exports of these items. Singapore was 13th and Malaysia 17th behind global leader Germany.

"Indeed, while the United States and Germany tend to specialise in the production of medical devices, China and Malaysia are most specialised in producing protective garments," it said in a May 5 report which showed the US and China were in the world's top four of both imports and exports of medical equipment needed during the coronavirus pandemic.

Mr Miroudot added during the NPF briefing that "countries are specialised in specific types of Covid-19 goods and depend on each other".

"The top exporter of face masks is China but if we look at intubation kits, the top exporter is the US, if we look at surgical gloves it is Malaysia. It is really a world of trade interdependencies," he said

https://www.straitstimes.com/asia/e...er-who-comes-first-in-global-race-for-vaccine
 
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