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http://www.bbc.com/news/magazine-35410148

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To restore sight to damaged eyes, doctors often need to transplant the cornea - the transparent covering of the iris and the pupil - from a donor's dead body. There is a worldwide shortage, but one country, Sri Lanka, is doing its best to satisfy demand, without seeking any reward - at least in this life.

Bandages cover Paramon Malingam's right eye. A tear appears in the left one. It is the relief of a very lucky man. "I thought I was going to live the rest of my life with one eye," he says.

Thirteen years ago, Malingam, a shop owner from central Sri Lanka, cut his eye with steel wire. Last year, he injured the same eye with a piece of wood. After both accidents, a new cornea from a donor saved his sight.

The cornea is the clear front part of the eye, which lets in light and helps focus images on the retina.

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When it's damaged, as a result of injury or disease, a person's sight deteriorates, sometimes to the point of blindness.

Often the only solution is a transplant, but in many countries donated corneas are in short supply - a situation aggravated by the fact that they have a brief shelf-life.

Harvesting of the eye must happen within a few hours of death and the cornea itself must be used on a patient within about four weeks, depending on the storage method.

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Malingam waited four days for his new cornea and is recovering at Sri Lanka's main eye hospital in the capital, Colombo.

"After the surgery, I was reborn to the world," he says.

A few doors down from his ward, Viswani Pasadi, a student, is preparing for a different kind of rebirth, by filling out a form at the National Eye Bank pledging her eyes when she dies.

Like most Sinhalese - who make up 75% of Sri Lanka's population - Pasadi is Buddhist. She believes in a cycle of birth, death and rebirth, and sees this donation as a sound investment in her future.

"If I donate my eyes in this life," she says, "I'll have better vision in my next life."

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Image captionViswani Pasadi holds her National Eye Bank certificate
Another who has taken this step is bookkeeper Preethi Kahlewatte.

"Whatever good things we do in this birth, that will take into the next birth," she explains. "When the person needs something, we like to donate. Without hands, we can work. Without legs, we can work. Without eyes, what can we do?"

According to the Eye Donation Society - a non-profit organisation founded by a young doctor, Hudson Silva, in 1961 - one in five Sri Lankans have pledged to donate their corneas. This does not include those, like Pasadi, who have signed up with the National Eye Bank, a separate institution which opened five years ago.

"It seems like I've signed a certificate for every human being in Sri Lanka," says the Eye Donation Society's medical director, Dr Siri Cassim, whose job includes adding his name to the decorative papers given to donors' families.

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The eagerness of Sri Lankans to offer their corneas to others means that the country has long harvested more than it needs and has been able to send the surplus to other countries.

The late Hudson Silva began this process in 1964, by packing a few eyes into an ice-filled thermos flask normally used for tea, and having them carried by hand on a flight to Singapore.

In 2014, his Society exported 2,551 corneas, including 1,000 to China, 850 to Pakistan, 250 to Thailand, and 50 to Japan.

The country's emergence as a major donor of corneas is largely down to Silva's dynamism. He made his first appeal for eye donations as a student in 1958, in a newspaper article co-authored with his wife and mother, urging Sri Lankans to "give life to a dead eye". The first corneas he received, the following year, he stored in his own refrigerator "along with the eggs and butter". Then in 1960 his mother died and it's said that Silva won the nation's heart by grafting her corneas on to the eyes of a poor farmer, and restoring his sight.

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Media caption Kiribathgoda Gnanananda Thero has donated a kidney and is encouraging others to donate organs too
Buddhist monks have also played a part in encouraging donations and teaching people to see them as an act of giving, or "dana", that will help them to be reincarnated into a better life.

The venerable Kiribathgoda Gnanananda Thero, founder of the Mahamevnawa Buddhist Monastery in Sri Lanka, told me a story from the Jataka, an ancient book of poems about the Buddha's earlier lives.

"In Buddha's previous life, he became a king. A blind beggar came to the palace and met the king. And he requested, 'Oh king, give me your eyes'. So he [Buddha] decided to give," he said.

The Buddha's surgeon then removed the Buddha's eyes, and transferred them to the beggar, restoring his vision.

"Generation to generation, we are listening to those kind of stories. So we are very encouraged to give our body parts to others," Thero says.

He himself has already donated a kidney to a woman with kidney disease.

The certificates handed out by the Eye Donation Society to those who pledge their corneas, explicitly allude to Buddhist teaching by carrying the words, "Let the donor have a good rebirth", though people from other religions have both made donations and received donated corneas.

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In Muslim countries it is generally forbidden to damage the human body, before or after death, so Pakistan and Egypt have been major recipients of Sri Lankan corneas. Malaysia, Nigeria, Sudan also feature on the list of more than 50 receiving countries.

Some of the biggest connections we make with people are through the eyes - they feel really personal
Cenay Said

The cornea is one of the easiest tissues to transplant as no matching is required between donor and recipient. It is bloodless tissue, taking oxygen directly from the air.

It is also possible to take a cornea from an elderly person, and graft it on to the eyes of a much younger one. If a donor is more than 80 years old there is a higher chance that the cornea will not be suitable, but it's reported that in one case the cornea of an 86-year-old Buddhist monk was given to a nine-year-old Jordanian boy.

Despite this, in the UK at least, the cornea is the tissue donors are most likely to exclude from the list of organs they are prepared to donate - 11% of the total, compared with less than 1% who refuse to donate their kidneys.

"I literally get this image of someone scooping out my eyeballs and it makes me really think," says one Londoner, Cenay Said, a camera assistant in the movie business.

"Some of the biggest connections we make with people are through the eyes. They feel really personal."

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Image copyright Getty Images

A cornea taken from Junius Jayewardene (president from 1978 to 1989) was split in two and grafted on to two Japanese patients - at least two former prime ministers also donated eyes @Nihonjin1051


This may be one reason why, according to the National Eye Research Centre in Bristol, there is a shortage of corneas in the UK - though as there is no national waiting list for corneas, unlike some other body parts, experts are unable to say with certainty how big the shortfall is.

When corneas are imported to the UK they tend to come from other European countries or the US - another major exporter - because the similarity in quality and safety standards makes it easier.

"This is not to say that the eye bank in Sri Lanka doesn't apply appropriate standards," says John Armitage of the UK's Corneal Transplant Service Eye Bank. "Rather it's a question of an eye bank in the UK having to fully audit the exporting eye bank to ensure compliance with the UK's standards."

Surprisingly perhaps, the removal of a dead person's eyes is not a problem for families that want an open coffin at the funeral.

Jayaratne Funerals in Colombo gets about six eyeless corpses a month.

"The embalmers take two cotton balls about the size of the eyeballs," says director Hasanga Jayaratne. "They soak it in embalming fluid and put it inside the eyes and use a bit of glue to shut the eyes."

Mourners are then able to see their loved-one one last time before the next life begins.

Corneas and blindness - facts and figures
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Image copyrightiStock
  • According to the WHO, 4% of the world's 39 million blind people suffer from corneal opacity (the scarring or clouding over of the cornea) while another 3% suffer from trachoma, a bacterial infection that results in damage to the cornea

  • Cataracts and glaucoma cause more cases of blindness, but trachoma is described as the main cause of preventable blindness

  • The main reasons for cornea transplants (keratoplasty) in Sri Lanka are the damage to the cornea as the result of an infection - sometimes including ulcers (infective keratitis) - or keratoconus, where the cornea becomes too thin and its shape is distorted

  • Sri Lanka took corneas from executed prisoners until 1956, when the death penalty was temporarily abolished - it was reintroduced in 1959, but there have been no executions since 1976

  • In the UK, the main reason for cornea transplants is a condition that mainly affects older people called Fuchs' dystrophy, which causes the cornea to swell and become cloudy - keratoconus is also a problem, though, affecting younger patients
 
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Kudos to those SriLankans :tup:

Massive Respect for the Sri Lankans.

Has to do with Buddhist principles mates.. Despite being poor countries both Burma and Sri Lanka continues to top most charitable nations (Voluntary not arbitrary) ranks each year due to their Theravada Buddhist traditions but rubs off on other denominations as well

http://www.theguardian.com/voluntar...ost-generous-nations-in-the-world-in-pictures

https://en.wikipedia.org/wiki/World_Giving_Index

@alaungphaya
 
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By Donating Eyes, Sri Lankans Give Sight to People Worldwide

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Amila Nilanga recuperates after a cornea transplant at the National Eye Hospital in Colombo, Sri Lanka. Sri Lankans donate large numbers of corneas both in their own country and abroad, partly because the donation is considered by Buddhists to be a meritorious act.




In the small island country, where the donation of one’s eyes is considered a meritorious act, more than 1 million people are registered donors. The nation has for decades provided excess corneas to foreign recipients, and many corneas not suitable for transplant are used for local and international research.

COLOMBO, SRI LANKA — Amila Nilanga battled for a decade with corneal blindness in his right eye. But now, at 28 years old, his vision is fully restored, thanks to a cornea transplant.

Nilanga waited on the transplant list for about three months before his surgery, but that wasn’t for a lack of a cornea. Due to a high rate of donations, Sri Lankans rarely have to wait for a cornea. In fact, the country exports all excess corneas and is a leading supplier of corneas to the world.

Instead, Nilanga, an electrical engineer, waited for his surgeon’s schedule at the state-run National Eye Hospital of Sri Lanka in Colombo to clear.

“It’s only a tissue, but I feel grateful to the donor,” he says. “This is a pious deed indeed. What can one do without sight?”

Sri Lanka, one of the world’s leading providers of corneas, has donated excess corneas to foreign patients for decades. The Buddhist practice of giving alms, especially donating a part of yourself to another, motivates many Sri Lankans to register to donate their eyes after they die. More than 1 million Sri Lankans are currently registered as eye donors.

The culture of eye donation in this island nation was pioneered by Dr. Hudson Silva, when, as a medical student in 1958, he wrote a newspaper article in which he called on Sri Lankans to donate their eyes.

The preparation and preservation of corneas is done within four hours, as in Sri Lanka, being a tropical country, decay sets in very fast.Janath Matara Arachchi, senior manager of the International Eye Bank
Silva garnered the support of Buddhist clergy in spreading his message, and the donation of one’s eyes was seen as a meritorious act, says Dr. M.H.S. Cassim, the medical director of the Sri Lanka Eye Donation Society, which Silva established as the Ceylon Eye Donation Society.

Stories of Buddha donating his blood and flesh in various incarnations have popularized the donation of blood, corneas and tissue in Sri Lanka.

Sri Lankans responded enthusiastically to Silva’s call.

When the Sri Lanka Eye Donation Society created the International Eye Bank in 1961, Silva was the first donor to register. His mother was the second, and when she died in 1963, he grafted her corneas to a farmer and restored his sight. That story convinced thousands of Sri Lankans to register with the society.

By the early 1960s, the country had more corneas than it needed, so Silva offered the excess to foreign hospitals. The first six corneas that were donated to a foreign hospital were carried by Silva in a thermos to Singapore in May 1964, on Vesak Day, which commemorates the birth, death and enlightenment of Buddha.

Although the majority of registered donors are Buddhists, Sri Lankans of all faiths are registered, Cassim says.

Between 1961 and mid-August 2016, the Sri Lanka Eye Donation Society provided 47,850 corneas to Sri Lankans and 73,085 corneas to people in 57 other countries. In addition, nearly 4,000 pairs of eyes, which did not have corneas suitable for transplant, were supplied for local and international research. There are now more than 1.3 million Sri Lankans registered with the society
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The National Eye Bank of Sri Lanka, which was set up in 2011 through a collaboration between the governments of Sri Lanka and Singapore, had donated more than 6,000 corneas to local and foreign recipients as of mid-August 2016. Both organizations provide the corneas free of charge, and foreign hospitals only pay export fees. The eye bank has 6,000 donors on its rolls.

Sri Lanka’s cornea supply is unusual. A global survey carried out in 2012 and 2013 by the U.S.-based National Institutes of Health revealed a lack of corneas around the world, with just one cornea available for every 70 needed. About 53 percent of the world’s population has no access to corneal transplantation, the report revealed.

Only the United States and Sri Lanka export large numbers of donated corneas, according to that report. And Sri Lanka’s population, at just over 20 million people, is a fraction of the U.S. population of nearly 320 million people.

Appeals for corneas reach the Sri Lanka Eye Donation Society and the National Eye Bank on a regular basis.

Dr. Priyani Dissanayake, a Sri Lankan now working with the Ministry of Health in Swaziland, lodged a formal request for corneas during a visit to Sri Lanka in August.

A large number of people between the ages of 20 and 30 in Swaziland are affected by a genetic disorder called keratoconus, which affects vision, Dissanayake says. Efforts to obtain corneas from other African countries were unsuccessful, she says.

“Since I am familiar with Sri Lankan culture and the donor programs, I am on a mission to request corneas from the National Eye Bank of Sri Lanka,” she says.

And Sri Lanka’s cornea supply shows no signs of shrinking.

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Kaushalya Fernando shows a certificate noting that she has registered to donate an eye. Fernando is among 1.3 million Sri Lankans registered with the Sri Lanka Eye Donation Society.

Kumala Wijeratne, GPJ Sri Lanka

Kaushalya Fernando is registered as a donor with the Sri Lanka Eye Donation Society.

“I was always keen in donating my eyes and my body to the medical faculty for the advancement of medical science,” says Fernando, 34.

She signed up to be a donor in June 2012, and she is registered to donate skin and other tissue as well.

She says her Buddhist faith prompted her to do so.

Fernando even corrected a squint in her eye, undergoing surgery in February, to ensure that upon death, she would donate a good pair of eyes, she says.

“When we offer alms, it has to be of good quality,” she says.

In addition to the registered donors, the Sri Lanka Eye Donation Society and the National Eye Bank work through the hospitals and doctors to encourage families to donate the eyes of a family member.

“The hospitals inform us when a death occurs, and we send a representative to meet with the family to obtain their permission and evaluate the eyes,” says Janath Matara Arachchi, senior manager of the International Eye Bank.

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Janath Matara Arachchi, of the Sri Lanka Eye Donation Society, holds a package of corneas, ready for export. Since 1961, the society has provided 47,850 corneas to Sri Lankans and 73,085 corneas to people in 57 other countries.


Since a cornea has to be transplanted within 14 days of its removal, the process moves quickly. The cornea is evaluated for quality, and tests are conducted to ensure that it’s not infected.

“The preparation and preservation of corneas is done within four hours, as in Sri Lanka, being a tropical country, decay sets in very fast,” Matara Arachchi says.

Removing and storing corneas is not a cheap process, says Fazna Ajward, a deputy manager at the National Eye Bank.

From procurement to preservation and transplant, the cost is around 35,000 rupees ($240) per cornea, she says. This cost is currently borne by the Singapore government.

The Sri Lanka Eye Donation Society, as a charity, depends completely on donations. It receives an average of about 450 corneas each month through next-of-kin donations and registered donors.

Kanchana Sandamali Adikari donated her husband’s eyes in 2015 after he died of pneumonia and a representative of the Sri Lanka Eye Donation Society contacted her.

“I gave permission for the removal of eyes, as it was an act of merit,” Adikari, 31, says.

Since then, she and her sister, Nimali Adikari, have registered as donors with the society.

“At first, we felt that since both of us have weak eyes and wear spectacles, we would be rejected,” Nimali Adikari, 33, says. “But then we came to understand that it’s the cornea that’s vital.”

The Sri Lanka Eye Donation Society has big plans for solving eye problems globally. Eliminating blindness is one, says Matara Arachchi, the International Eye Bank manager.

Meanwhile, the National Eye Bank is developing uses for donated eyes that don’t meet transplant standards.

“We are in the process of developing a corneal research laboratory, so that corneas that are not considered to be of high standard could be used for research,” says Ajward, the National Eye Bank deputy manager.
 
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