Dr Tahir Shamsi says passive immunisation can treat coronavirus patients

[Dr. Strangelove]

Many young will be available within Pakistan a couple of weeks later.. I don't expect many young people dying from this disease.. so they will be available.


Yeah, he is not the first one.. that's why he said Chinese are saving lives through this method since February.
He was confident in today's program..
I think he is suggesting to use on very sick patients.. which means the patient's body has started identifying the disease.. but it requires help which can be given in the form of plasma of a recovered patient..

What do you think doc?

It will work. But it would be a stop gap measure. Yes it would save lives that other wise couldnt be saved and should be used as much as it could but this is not something groundbreaking. It will require a lot of effort and a lot of healthy recovered individuals.

What i m afraid of is that Covid-19 is here to stay and it will hit us again and again over the next 10-18 months. All it would need is one carrier to start everything again. And God forbid if it develops behavior like influenza even a vaccine wont save us. It is already established it has at least another strain and could develop more so even the Long Inevitable Herd immunity wont help us.

Best short term goal right now is to get an effective Antiviral drug in market as soon as possible so supportive treatment can be done more effectively. What we need is to use what industrial base we have is to start making Ventilators we will need a lot in case things blow up and build capacity that will actually save tonnes of lifes. With them we can save a lot of critical patients. US has over 200,000 they estimate a requirements of over 500,000 more. Compare with us we have just 2200 with varying degree of availability some of them arnt even worth using importing from china alone wont be enough to cover local requirement.

 

[PakSword]

It will work. But it would be a stop gap measure. Yes it would save lives that other wise couldnt be saved and should be used as much as it could but this is not something groundbreaking. It will require a lot of effort and a lot of healthy recovered individuals.

What i m afraid of is that Covid-19 is here to stay and it will hit us again and again over the next 10-18 months. All it would need is one carrier to start everything again. And God forbid if it develops behavior like influenza even a vaccine wont save us. It is already established it has at least another strain and could develop more so even the Long Inevitable Herd immunity wont help us.

Best short term goal right now is to get an effective Antiviral drug in market as soon as possible so supportive treatment can be done more effectively. What we need is to use what industrial base we have is to start making Ventilators we will need a lot in case things blow up.

Of course it's not ground breaking..

Regarding the number of recovered individuals.. I think Dr. Shamsi and government has done some homework already.. lets see what happens..

Even if it's a stop gap measure, it will give a lot of needed relief to our hospitals and intensive care units.

 

[BHarwana]

Dr Tahir Shamsi, the head of National Institute of Blood Diseases said, “The body of a COVID-19 patient creates antibodies to fight off the virus. These antibodies in the blood of a recovered patient could be used to boost the immunity of the newly infected people.”

According to the details, Top hematologist and transplant surgeon of Pakistan said that the blood of recovered patients of coronavirus– the mysterious respiratory illness caused by the novel COVID-19 which could be used to slow the spread of the deadly contagion which has killed more than 10,000 people and affected 254,801 others worldwide.

“We can save precious lives using this technique,” Dr Shamsi said while adding that the National Institute of Blood Diseases is fully equipped to successfully use this technique. “Doctors have saved hundreds of lives with the help of this technique in China since February,” he added.

While talking to the newspaper he further said, “A vaccine works by training the immune system to recognise and combat pathogens – either viruses or bacteria – by creating antibodies in the blood. And when the pathogens enters the body, the antibodies already present in the blood successfully fight it off.”

@Mangus Ortus Novem @masterchief_mirza @jaibi @Ace of Spades @Syed Hammad Ahmed @SIPRA @Path-Finder @Areesh @Verve @BHarwana @Blacklight @Dubious

https://www.bolnews.com/health/2020...s-patients-says-top-hematologist-of-pakistan/

Yes they can be used but will be extracted from bone marrow. In China the first patients who got healed donated their anti-bodies voluntarily to test them on other patients. It is a known and used technique.

 

[masterchief_mirza]

Whatever happens over the coming months, the world will be a changed place because this virus appears to have a more significant mortality and hospitalization rate (on itu wards) compared to flu, and is similarly infectious. It drains high end resources much more significantly than flu. If it mutates and evades vaccine programmes then we're in bigger trouble.

Posters mentioning a full industrial shift being needed for years to come in order to counter this threat are spot on.

 

[Path-Finder]

there are alot of things and ideas being formed on this pandemic. i heard the Russians have made some breakthrough with covid19 as well. but the suggestion made is a good one and honestly at this time any measure to save lives should be done.

 

[Ace of Spades]

It will work. But it would be a stop gap measure. Yes it would save lives that other wise couldnt be saved and should be used as much as it could but this is not something groundbreaking. It will require a lot of effort and a lot of healthy recovered individuals.

What i m afraid of is that Covid-19 is here to stay and it will hit us again and again over the next 10-18 months. All it would need is one carrier to start everything again. And God forbid if it develops behavior like influenza even a vaccine wont save us. It is already established it has at least another strain and could develop more so even the Long Inevitable Herd immunity wont help us.

Best short term goal right now is to get an effective Antiviral drug in market as soon as possible so supportive treatment can be done more effectively. What we need is to use what industrial base we have is to start making Ventilators we will need a lot in case things blow up and build capacity that will actually save tonnes of lifes.

With respiratory viruses it's mostly not long term immunity that is developed, unless after severe infection; and in those instances body develops rather long term immunity. So a silver lining, which is my personal opinion as a medical professional, is that the ones who gets severely sick during this first wave probably won't get reinfection again. The ones who won't get lower respiratory tract involved this time around will have bigger chance of reinfection, though very unlikely after few month since the short term immunity usually lasts a year or so, but varies person to person and lots of factors. But coming to the point, those with mild infection this time around, probably will be fine during the next time around as well if re-infected. And indeed herd immunity won't work the way it's being put. But there would be a better recoveries second time around if majority population gets sick this time; which even we can't afford this time due to lack of every basic health care facility and there will be high mortality rate. May Allah protect everyone.

 

[denel]

that goes without saying. you cant expect that in today's world some institute will undergo the process of immunoglobulins without checking for other diseases.

yes, but let us not forget in the haste to deliver. short corners leads to more issues as the HIV cases in kids recently have shown. Take time but do it properly.

 

[PakSword]

On a slightly separate note, why does his name ring a bell? Is this the same haematologist who treated nawaz Sharif's platelets??

Yes!

With respiratory viruses it's mostly not long term immunity that is developed, unless after severe infection; and in those instances body develops rather long term immunity. So a silver lining, which is my personal opinion as a medical professional, is that the ones who gets severely sick during this first wave probably won't get reinfection again. The ones who won't get lower respiratory tract involved this time around will have bigger chance of reinfection, though very unlikely after few month since the short term immunity usually lasts a year or so, but varies person to person and lots of factors. But coming to the point, those with mild infection this time around, probably will be fine during the next time around as well if re-infected. And indeed herd immunity won't work the way it's being put. But there would be a better recoveries second time around if majority population gets sick this time; which even we can't afford this time due to lack of every basic health care facility and there will be high mortality rate. May Allah protect everyone.

Wow,.. very nicely explained.

 

[BHarwana]

@PakSword bro it is a very long and high effort process that require a lot of resources. It can be used on few critical patients you cannot facilitate everyone with it even China was not able to do it. They only used it to save more critical ones.

 

[masterchief_mirza]

With respiratory viruses it's mostly not long term immunity that is developed, unless after severe infection; and in those instances body develops rather long term immunity. So a silver lining, is that the ones who gets severely sick during this first wave probably won't get reinfection again. The ones who won't get lower respiratory tract involved this time around will have bigger chance of reinfection, though very unlikely after few month since the short term immunity usually lasts a year or so, but varies person to person and lots of factors. But coming to the point, those with mild infection this time around, probably will be fine during the next time around as well if re-infected. And indeed herd immunity won't work the way it's being put. But there would be a better recoveries second time around if majority population gets sick this time; which even we can't afford this time due to lack of every basic health care facility and there will be high mortality rate. May Allah protect everyone.

Very concerning because it seems as though being beyond a certain age and having comorbidities will always now result in susceptibility to this virus and its annual variations. It really is like a "much scarier influenza".

Yes, having it at full whack will confer some resistance, but what must one go through to gain that resistance?! Now, everyone entering into the "vulnerable group" each year will have to run this gauntlet, as the virus mutates year after year. Some of the group will survive and some simply will not - and this episode will repeat itself annually, mitigated potentially only by a vaccination programme.

 

[MastanKhan]

Please ensure that the serum taken is checked and rechecked for other issues - hiv/hep first.

Hi,

Thank you Denel for bringing out a very interesting and unique concern---.