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This is research paper, you can find the original one at
http://www.chinaxiv.org/user/download.htm?id=30147
Findings
Eight coding-regions have 120 substitution sites, including 79 non-synonymous and 40 synonymous substitutions. Forty-two non-synonymous substitutions changed the biochemical property of amino acids. No combinations were detected. Fifty-eight haplotypes were classified into five groups: 31 haplotypes were found in samples from China and 31 in samples from other countries. The rooted network suggested that H13 and H35 were ancestral haplotypes, and H1 (which with its descendants included all samples from the Hua Nan market) was derived from the H3 haplotype. Population size of SARS-CoV-2 was estimated to have had a recent expansion on 6 January 2020, and an early expansion on 8 December 2019.
Interpretation
Genomic variations of SARS-CoV-2 are still low in comparisons with published genomes of SARS-CoV and MERS-CoV. Phyloepidemiologic analyses suggested that the SARS-CoV-2 source at the Hua Nan market was imported from elsewhere. The crowded market then boosted SARS-CoV-2 circulation and spread it to the whole city in early December 2019. Furthermore, phylo epidemiologic approaches have recovered specific directions of human-to-human transmissions and the sources for international infected cases.
http://www.chinaxiv.org/user/download.htm?id=30147
Findings
Eight coding-regions have 120 substitution sites, including 79 non-synonymous and 40 synonymous substitutions. Forty-two non-synonymous substitutions changed the biochemical property of amino acids. No combinations were detected. Fifty-eight haplotypes were classified into five groups: 31 haplotypes were found in samples from China and 31 in samples from other countries. The rooted network suggested that H13 and H35 were ancestral haplotypes, and H1 (which with its descendants included all samples from the Hua Nan market) was derived from the H3 haplotype. Population size of SARS-CoV-2 was estimated to have had a recent expansion on 6 January 2020, and an early expansion on 8 December 2019.
Interpretation
Genomic variations of SARS-CoV-2 are still low in comparisons with published genomes of SARS-CoV and MERS-CoV. Phyloepidemiologic analyses suggested that the SARS-CoV-2 source at the Hua Nan market was imported from elsewhere. The crowded market then boosted SARS-CoV-2 circulation and spread it to the whole city in early December 2019. Furthermore, phylo epidemiologic approaches have recovered specific directions of human-to-human transmissions and the sources for international infected cases.
