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Chinese scientist announces world's first gene-edited babies born

So the babies are born immune to HIV since the father is HIV positive. This should be a good thing. What the **** is wrong with so called educated Chinese audience. They sound like a bunch if western liberals.

Let the man continue his research. If this was performed by a western scientist he could be the man of the year in Times magazine

As far as I know, the research is now paused by the related ministry, not stopped, which is a good thing. I think there will be some more regulatory measures and then research will be allowed to continue.
 
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https://news.sky.com/story/amp/chin...troversial-baby-gene-editing-project-11566953

Seems like there's a law against gene editing.

Do we need to inject twins with HIV to see if experiment is a success?

No, that would be immoral.

So, there will be no practical way to see if the experiment is success or not. The only way is to perform the same procedure on a greater number of embryos and then track those people throughout their lives. If, int he end, contrary to the national average, none of them contracts HIV, the procedure would be deemed a success.

Less immoral way would be to perform in animals, which, I believe they have already done so.
 
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Do we need to inject twins with HIV to see if experiment is a success?
The assumption is that if one parent is HIV positive, then the embryo would be -- or should be -- HIV positive as well.

In the case of He Jiankui's experiment, the father is HIV positive, the mother is HIV negative. The situation is called a 'discordant' couple. One positive and partner is negative.

So what is the question...

1- Prevent HIV transmission from mother to fetus ?
2- Allow HIV transmission while pregnancy but alter the fetus's genes to be immunized ?

There are current methods where the risk of HIV transmission to the fetus is about %2.

http://americanpregnancy.org/pregnancy-complications/hiv-aids-during-pregnancy/
...new treatments can reduce the risk of a treated mother passing HIV to her baby to a 2 percent or less chance.
However, there are many discordant couples where the child is negative despite the mother who had no treatment while pregnant.

How do we know if the discordant couple in He's experiment will produce an HIV negative child? We do not.

So to really prove He's experiment as successful, we would have to deliberately infect one of the twins with the HIV virus and see if the gene editing work.
 
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No, that would be immoral.

So, there will be no practical way to see if the experiment is success or not. The only way is to perform the same procedure on a greater number of embryos and then track those people throughout their lives. If, int he end, contrary to the national average, none of them contracts HIV, the procedure would be deemed a success.

Less immoral way would be to perform in animals, which, I believe they have already done so.

The assumption is that if one parent is HIV positive, then the embryo would be -- or should be -- HIV positive as well.

In the case of He Jiankui's experiment, the father is HIV positive, the mother is HIV negative. The situation is called a 'discordant' couple. One positive and partner is negative.

So what is the question...

1- Prevent HIV transmission from mother to fetus ?
2- Allow HIV transmission while pregnancy but alter the fetus's genes to be immunized ?

There are current methods where the risk of HIV transmission to the fetus is about %2.

http://americanpregnancy.org/pregnancy-complications/hiv-aids-during-pregnancy/

However, there are many discordant couples where the child is negative despite the mother who had no treatment while pregnant.

How do we know if the discordant couple in He's experiment will produce an HIV negative child? We do not.

So to really prove He's experiment as successful, we would have to deliberately infect one of the twins with the HIV virus and see if the gene editing work.

You guys have come to the same conclusion as me, infect them. Which naturally is a bad idea. Gambit, one parent is HIV positive, interesting, but as you stated other treatments are available to lower HIV transmission. Can't they use IVF, if dad is HIV carrier?

Generally HIV threat for the wider population is low because it is preventable. Gene editing to eliminate certain cancers would be more welcome because some are inherited.
 
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You guys have come to the same conclusion as me, infect them. Which naturally is a bad idea. Gambit, one parent is HIV positive, interesting, but as you stated other treatments are available to lower HIV transmission. Can't they use IVF, if dad is HIV carrier?

Generally HIV threat for the wider population is low because it is preventable. Gene editing to eliminate certain cancers would be more welcome because some are inherited.
Maybe the couple could not afford the HIV treatment for the mother to prevent transmission to the fetus? Then He offered this gene editing treatment for free?
 
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in 100 years, with advancement of quantum computer, human will achieve remarkable result with gene editing to the point of we can create human body or reengineers new life.
this will be a new normal.
 
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in 100 years, with advancement of quantum computer, human will achieve remarkable result with gene editing to the point of we can create human body or reengineers new life.
this will be a new normal.
Too bad no one here will see if that will happen.
 
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Good, the already smart Chinese will be smarter in the future and widen the gap between them and the dumb vietnamese and indians.
 
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Can China give this technology to india please, so they can make some sane babies?


Chinese scientist announces first gene-edited babies born

CGTN

Updated 2018-11-26


7f123a7fa0f54d839424aa07af3ff14f.jpg


Chinese scientist He Jiankui said that he helped make the world's first genetically edited babies – twin girls born this month whose DNA he altered with a powerful new tool capable of resisting possible future infection with HIV, the AIDS virus, according to People's Daily.


He revealed it in Hong Kong, one day ahead of an international conference on gene editing that is scheduled from Tuesday to Thursday.

He's team used the CRISPR-Cas9 genome editing tool that makes it possible to precisely locate and operate on DNA to supply a needed gene or disable one that's causing problems.

However, AP news agency said that the announcement could not be independently confirmed, as the it has not been published in a journal, as usually done for any successful research. AP had an exclusive interview with the scientist earlier.

Gene-editing can also easily raise moral and ethical problems. Some scientists condemned such "experiment on human beings," while others, including one famed geneticist, Harvard University's George Church, defended the attempting of gene editing for HIV, calling it "justifiable".

https://news.cgtn.com/news/3d3d514f7759444f30457a6333566d54/share_p.html
 
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