Viet
ELITE MEMBER
- Joined
- Jun 18, 2012
- Messages
- 29,950
- Reaction score
- 0
- Country
- Location
NEWS PROVIDED BY
SUNSTAR Joint Stock Company
28 Apr, 2020, 08:00 BST
HANOI, Vietnam, April 28, 2020/PRNewswire/ -- Production and launch of the test kit RT-PCR COVID-19 Thai Duongwill take place at the end of April 2020 and are carried out by Vietnamese science and technology company SUNSTAR Joint Stock Company.
The production of the test kit "RT-PCR COVID-19 Thai Duong" by Vietnamese science and technology company SUNSTAR JSC (Sao Thai Duong) will start at the end of April 2020. The test kit has the ability to addresses false-negative test results.
According to Worldometers, there are a total of seventeen million COVID-19 tests being performed globally and of them about two million results are positive which means more than ten million are negative. These negative test results are a source of increasing concern as in many cases, the patients clearly display the symptoms but still their tests show negative result. Studies based on 866 tests performed in China and published on MedRXiV show that suspected false-negative test results can be as high as 30%. McLaren, a Miami-based American health management firm, claims that approximately 20% of patients who have been tested in clinics have received false-negative results.
Experts estimate that false-negative results can cause damages globally amounting to billions of dollars. This is an issue which must be addressed if efforts to stop the pandemic are to be successful.
The primary cause of false-negative result is errors being committed when samples are taken. As a solution to this problem, experts of the National Institute for Control of Vaccine and Biologicals of Vietnam (NICVB) have developed a new RT-PCR diagnostic kit under the name RT-PCR COVID-19 Thai Duong, which besides the use of diagnostic target genes, contain an internal control to detect human DNA in samples. Clinical samples which have been incorrectly collected will give insufficient DNA result and will be excluded. This way, there will be a significant improvement of the percentage of false-negative results.
Based on a research project at the NICVB, during the past three months, the test kit has completed trials at the National Institute of Hygiene and Epidemiology (NIHE) and the National Hospital for Tropical Diseases (NHTD) using 150 negative clinical samples, 35 positive samples, and 30 mimic positive samples.
Dr. Doan Huu Thien, the head of the research group, says: "The new test kit has proved to have a 100% sensitivity, which detect the virus even at low levels, 100% specificity, which prevents cross reactions with other viruses and bacteria in the human respiratory tracks, and agreement ratio as 100% following the process recommended by WHO. It can even detect errors in the collection of samples as well as safeguarding the entire diagnostic process. The kit includes 9 primer and probe sequences to detect 3 target genes of beta coronavirus including SARS-CoV, SARS-CoV-2 and bat SARS-CoV. Amplification result and the limit of detection of 3 target genes equal to Realtime RT-PCR multiple primer of the biological kit."
SUNSTAR Joint Stock Company
28 Apr, 2020, 08:00 BST
HANOI, Vietnam, April 28, 2020/PRNewswire/ -- Production and launch of the test kit RT-PCR COVID-19 Thai Duongwill take place at the end of April 2020 and are carried out by Vietnamese science and technology company SUNSTAR Joint Stock Company.
The production of the test kit "RT-PCR COVID-19 Thai Duong" by Vietnamese science and technology company SUNSTAR JSC (Sao Thai Duong) will start at the end of April 2020. The test kit has the ability to addresses false-negative test results.
According to Worldometers, there are a total of seventeen million COVID-19 tests being performed globally and of them about two million results are positive which means more than ten million are negative. These negative test results are a source of increasing concern as in many cases, the patients clearly display the symptoms but still their tests show negative result. Studies based on 866 tests performed in China and published on MedRXiV show that suspected false-negative test results can be as high as 30%. McLaren, a Miami-based American health management firm, claims that approximately 20% of patients who have been tested in clinics have received false-negative results.
Experts estimate that false-negative results can cause damages globally amounting to billions of dollars. This is an issue which must be addressed if efforts to stop the pandemic are to be successful.
The primary cause of false-negative result is errors being committed when samples are taken. As a solution to this problem, experts of the National Institute for Control of Vaccine and Biologicals of Vietnam (NICVB) have developed a new RT-PCR diagnostic kit under the name RT-PCR COVID-19 Thai Duong, which besides the use of diagnostic target genes, contain an internal control to detect human DNA in samples. Clinical samples which have been incorrectly collected will give insufficient DNA result and will be excluded. This way, there will be a significant improvement of the percentage of false-negative results.
Based on a research project at the NICVB, during the past three months, the test kit has completed trials at the National Institute of Hygiene and Epidemiology (NIHE) and the National Hospital for Tropical Diseases (NHTD) using 150 negative clinical samples, 35 positive samples, and 30 mimic positive samples.
Dr. Doan Huu Thien, the head of the research group, says: "The new test kit has proved to have a 100% sensitivity, which detect the virus even at low levels, 100% specificity, which prevents cross reactions with other viruses and bacteria in the human respiratory tracks, and agreement ratio as 100% following the process recommended by WHO. It can even detect errors in the collection of samples as well as safeguarding the entire diagnostic process. The kit includes 9 primer and probe sequences to detect 3 target genes of beta coronavirus including SARS-CoV, SARS-CoV-2 and bat SARS-CoV. Amplification result and the limit of detection of 3 target genes equal to Realtime RT-PCR multiple primer of the biological kit."
