Interesting characteristic of the Wuhan Coronavirus

[FairAndUnbiased]

Umm, maybe next time you should read what I replied to before open your mouth water gun blazing.

He specifically mentioned Bat. which is an mammal, which is what I refer to (and what you claimed) as such, which is a dig at his "temperature animal" I though you are smart enough to digest I know the fact that there are warm blooded birds, lizard by referring it to "warm blooded ANIMAL" but I guess you are too stupid to pick that up.



The rest of your post. Well, No reply value what-so-ever.

I don't read your drivel except to use it to expose your ignorance.

 

[KungFuLee]

I don't read your drivel except to use it to expose your ignorance.

Yeah, as much as using what you learn on Wikipedia on Benford's law and accuse me of copying them on Wikipedia, right?

LOL Base 10 on cooking 28 days data, (it must be Day 1 30%, Day 2 17%, Day 3 13% …….Day 10 0%, day 11 0% day 12 0%) I laugh out very loud when I hear that, and I am still laughing when I type this... LOL damn, man, if you have half a brain, you would have figured that out. LOL

What a stupid guy, saying exposing me only exposing himself......

 

[FairAndUnbiased]

Yeah, as much as using what you learn on Wikipedia on Benford's law and accuse me of copying them on Wikipedia, right?

LOL Base 10 on cooking 28 days data, (it must be Day 1 30%, Day 2 17%, Day 3 13% …….Day 10 0%, day 11 0% day 12 0%) I laugh out very loud when I hear that, and I am still laughing when I type this... LOL damn, man, if you have half a brain, you would have figured that out. LOL

What a stupid guy, saying exposing me only exposing himself......

I don't understand this barking.

 

[Zsari]

Actually, it does....If you know how virology works.

A virus is a simple DNA mechanism, which mean without a host, a virus cannot survive. Which mean if a virus want to survive, they have to infect something, or someone.

A virus usually try to infect people with geographical proximity. If a virus is found in Africa, then the natural reservoir would be population in Africa. Which mean the virus would either try to infect local population to survive, or local population will get infected by whatever mean (like eating infected pork, monkey or so on) and get the virus that way. What that mean is local population would have infected a least threaten form (or mild form) of the original virus, and then get antibodies for it, and kills off the virus, however, what virus does in order to survive is to adapt to the surrounding antibodies which is gene specific. So by each mutation, they are going to be more adaptive to the local population in order to survive longer to infect other, because that is their way of reproduction.

Hence you will find local virus usually target local population, like Ebola usually wreck the local African population but white people got infected seldom dies. (I think the ratio, I read somewhere is about 63% of infected African dies, versus 26% of other races)

And Zika did spread to USA or Even Europe, they are not local like you said, that is because you are describing the Zoonotic stage (cross species infection). Once it hit human to human, which zika does, it does not limited on mosquito, but rather human movement between population. Another point you need to notice is that South American also have a huge white or mixed population. They aren't as affected as the American Indian in South America.

You seem to be confused. SARS/Coronavirus utilizes ACE2 receptor, both Ebola & Hepatitis A utilizes TIM1 receptor, Zika utilizes AXL receptors, etc. I have yet to find any publication that points to TIM1 being more common in African nor AXL being more prevalent in Hispanics.

There is no advantage in mutation that targets ACE2 receptor as compare to for example TIM1 as Asians are susceptible equally to both. The coronavirus will do just as well if not better to utilize TIM1 receptor as we all know Hepatitis A is very wild spread in Asia. The only "advantage" is the ACE2 receptor is much less common in white, a characteristics that is completely irrelevant to the virus for its survival in the local population. Your theory is using the wrong frame of reference.

What you find being more common is very superficial as Ebola mortality rate has very much to do with the medical development in the Africans states. Zika can be transmitted only through sex and pregnancy without the mosquito. It's transmission is certainly very much hampered without its primary mean. Matter fact, according to US statistics, the birth defects due to Zika is higher in US states than US territory such as Puerto Rico that shares closer genetic maps with Brazilians. And that is contradictory to your theory.

 

[FairAndUnbiased]

You seem to be confused. SARS/Coronavirus utilizes ACE2 receptor, both Ebola & Hepatitis A utilizes TIM1 receptor, Zika utilizes AXL receptors, etc. I have yet to find any publication that points to TIM1 being more common in African nor AXL being more prevalent in Hispanics.

There is no advantage in mutation that targets ACE2 receptor as compare to for example TIM1 as Asians are susceptible equally to both. The coronavirus will do just as well if not better to utilize TIM1 receptor as we all know Hepatitis A is very wild spread in Asia. The only "advantage" is the ACE2 receptor is much less common in white, a characteristics that is completely irrelevant to the virus for its survival in the local population. Your theory is using the wrong frame of reference.

What you find being more common is very superficial as Ebola mortality rate has very much to do with the medical development in the Africans states. Zika can be transmitted only through sex and pregnancy without the mosquito. It's transmission is certainly very much hampered without its primary mean. Matter fact, according to US statistics, the birth defects due to Zika is higher in US states than US territory such as Puerto Rico that shares closer genetic maps with Brazilians. And that is contradictory to your theory.

he doesn't know what he's talking about. when discussing medical statistics and accounting, he asks about "why use base 10".

Why base 10?

this guy is an absolute joke. Mental capability of a 5 year old. You can tell from the way he types, like ESL, but supposedly "Australian". lmao.

 

[KungFuLee]

I don't understand this barking.

Yeah, that's because you pretend to know Benford's law.

 

[FairAndUnbiased]

Yeah, that's because you pretend to know Benford's law.

when did I say anything about Benford's law? you were the one that brought it up first on page 2. The term "Benford's Law" never came up before you mentioned it. I never claimed any knowledge of it. I simply asked you how it is applied in this circumstance. You did alot of dodging and weaving, hoping I'd forget after reading a bunch of your nonsense, but I don't, and you still didn't answer the question.

 

[KungFuLee]

he doesn't know what he's talking about. when discussing medical statistics and accounting, he asks about "why use base 10".

lol, yet, you still cannot tell me why using Base 10 in this case is wrong. LOL

this guy is an absolute joke. Mental capability of a 5 year old. You can tell from the way he types, like ESL, but supposedly "Australian". lmao.

I never claim myself to be an Australian, I am from Hong Kong, of course my English is ESL level. Or you are purporting yourself to be an "American" when you yourself also type crappy English. lol

Now I think you are seeing things.

when did I say anything about Benford's law? you were the one that brought it up first on page 2. The term "Benford's Law" never came up before you mentioned it. I never claimed any knowledge of it. I simply asked you how it is applied in this circumstance. You did alot of dodging and weaving, hoping I'd forget after reading a bunch of your nonsense, but I don't, and you still didn't answer the question.

So, do tell me why Base 10 is wrong?

I did answered your question, but you are just too stupid to understand.

You seem to be confused. SARS/Coronavirus utilizes ACE2 receptor, both Ebola & Hepatitis A utilizes TIM1 receptor, Zika utilizes AXL receptors, etc. I have yet to find any publication that points to TIM1 being more common in African nor AXL being more prevalent in Hispanics.

There is no advantage in mutation that targets ACE2 receptor as compare to for example TIM1 as Asians are susceptible equally to both. The coronavirus will do just as well if not better to utilize TIM1 receptor as we all know Hepatitis A is very wild spread in Asia. The only "advantage" is the ACE2 receptor is much less common in white, a characteristics that is completely irrelevant to the virus for its survival in the local population. Your theory is using the wrong frame of reference.

What you find being more common is very superficial as Ebola mortality rate has very much to do with the medical development in the Africans states. Zika can be transmitted only through sex and pregnancy without the mosquito. It's transmission is certainly very much hampered without its primary mean. Matter fact, according to US statistics, the birth defects due to Zika is higher in US states than US territory such as Puerto Rico that shares closer genetic maps with Brazilians. And that is contradictory to your theory.

Again, the advantage for the virus (COVID-19) to mutate that target ACE2 is because it was cultured in an Asian setting (namely Chinese) around, what would you think it's easier to find, an Asian in China or a white man in China to be their host? And hence forth, they need to mutate to target the one group of people that ensure they will survive in the next mutation.

Almost all zoonotic virus are like that....

I really don't know why is it so hard to understand what is the advantage for a virus that come from Asia region to have receptor target Asian people. I mean, where do most Asian people live? Asia of course......

 

[Zsari]

The UK guy fighting for his life in Thailand is a white male. Ash Shorely.

View attachment 605883

View attachment 605880

He had to be carried by specialized seaplane because his damaged lungs could not cope with high altitude travel

"Studies show the Wuhan Coronavirus (2019-nCov) specifically targets the ACE2 protein that is 5x more prevalent in Asian males, resulting in easier transmission and higher morbidity rates"

That does not translate into other ethnicity being immune to the virus, unfortunately.

Again, the advantage for the virus (COVID-19) to mutate that target ACE2 is because where it cultured, it have many Asian (namely Chinese) around, what would you think it's easier to find, an Asian in China or a white man in China to be their host? And hence forth, they need to mutate to target the one group of people that ensure they will survive in the next mutation.

ACE2 is NOT the most common receptors in Asian when compared to other receptors. It is the most common receptors in Asian when compared to the same receptor in other ethnicity. Do you understand the difference in the two statement?

 

[KungFuLee]

ACE2 is NOT the most common receptors in Asian when compared to other receptors. It is the most common receptors in Asian when compared to the same receptor in other ethnicity. Do you understand the difference in the two statement?

I know what you are saying you mean ACE2 is the distinguish factor (or something along that line) when you compare Asian and other ethnicity.

If you ask me why this particular receptor is targeting, I do not have any idea why, I don't think anyone did. How do you actually define genetic mutation? All I know is, you have a trigger event, a mutation occurred and in this case, ACE2 is altered. Does that have it own importance? I will be more inclined to believe this is a random event more than a man-made event.

 

[SEAISI]

this guy is an absolute joke. Mental capability of a 5 year old. You can tell from the way he types, like ESL, but supposedly "Australian". lmao.

This retard is making Australians look bad...what a cun7

 

[KungFuLee]

This retard is making Australians look bad...what a cun7

A.) I am not an Australian.
B.) So are you.

Just by swearing does not make your statement true or stronger. And that applies to the person you replies to.

 

[riscol]

An accountant having lots of free time using jargon explaining viral topics.

 

[StormBreaker]

Studies show the Wuhan Coronavirus (2019-nCov) specifically targets the ACE2 protein that is 5x more prevalent in Asian males, resulting in easier transmission and higher morbidity rates

Studies show the virus should be significantly less deadly outside of Asia due to the virus primarily spreading to and killing Asian males.

Similar to SARS, 2019-nCov targets the ACE2 protein in lung cells. This protein is predominantly found in Asian males.

2.5% of Asian donor cells express ACE2 and only .47% of black and white donor cells. The virus needs ACE2 to inject RNA. Thus the more ACE2 expressed in cells the more easily the virus is transmitted and the higher the morbidity rate.

This can be seen by the virus mostly infecting and killing males (3:1 ratio of infection) and having difficulty spreading outside of Asia.

ACE2 risk:

https://pbs.twimg.com/media/EPnyPKvX0AAtdJ0?format=png&name=900x900

Source studies:

https://www.ncbi.nlm.nih.gov/m/pubmed/16282461/

https://www.biorxiv.org/content/10.1101/2020.01.26.919985v1.full

https://www.sciencedaily.com/releases/2020/01/200131114755.htm

https://asm.org/Press-Releases/2020/Novel-Coronavirus-2019-nCoV-Receptors-Shows-Simila

https://www.cell.com/fulltext/S0092-8674(03)00976-0

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229671/

https://www.nature.com/articles/d41586-020-00190-6

https://www.ncbi.nlm.nih.gov/m/pubmed/18554741

https://pga.gs.washington.edu/gty_data/ace2/

http://ncbi.nlm.nih.gov/snp/rs1978124 East Asian C=0.99 African C=0.900 South Asian C=0.78 American C=0.71 Europe C=0.53

https://ncbi.nlm.nih.gov/snp/rs714205 East Asian G=0.54 South Asian G=0.47 American G=0.30 Europe G=0.20 African G=0.101

http://ncbi.nlm.nih.gov/snp/rs879922 East Asian G=0.96 South Asian G=0.71 American G=0.72 Europe G=0.65 African G=0.454

http://ncbi.nlm.nih.gov/snp/rs2048683 East Asian G=0.99 African G=0.807 South Asian G=0.80 American G=0.75 Europe G=0.65

http://ncbi.nlm.nih.gov/snp/rs1877752 East Asian C=0.98 South Asian C=0.71 American C=0.71 Europe C=0.64 African C=0.453

ncbi.nlm.nih.gov/snp/rs233575 East Asian A=1.00 African A=0.988 South Asian A=0.82 American A=0.79 Europe A=0.66

So does that mean that asian males are by birth having lung diseases ?

 

[zectech]

Yes, its one possibility. But it doesnt expell the theory, that nCov COULD be artificial. The intention COULD be just for testing or sending a "message" or just to weakening the economy.