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A little alcohol cleans brain of waste, say scientists
Rosamma Thomas| TNN | Feb 6, 2018, 20:20 IST
62
JAIPUR: Have you found your teetotaler friends a bit boring? Now here's scientific evidence to show that a little alcohol is just the best thing for the brain. A new study in the journal Scientific Reports shows that low levels of alcohol consumption tamp down inflammation and helps the brain clear away toxins, including those associated with Alzheimer's disease.
Website Science Daily quoted Maiken Nedergaard, lead author of this study and co-director of the Center for Translational Neuromedicine at the University of Rochester Medical Center (URMC) as saying: "Prolonged intake of excessive amounts of ethanol is known to have adverse effects on the central nervous system. However, in this study we have shown for the first time that low doses of alcohol are potentially beneficial to brain health, namely it improves the brain's ability to remove waste."
Excessive alcohol consumption is shown to be addictive and a health hazard. In many parts of rural Rajasthan, for instance, women have been campaigning for shuttering the local liquor vend. However, studies have shown now that lower levels of drinking lead to reduced risk of cardiovascular diseases and a number of cancers.
Nedergaard's research focuses on the glymphatic system, the brain's unique cleaning process that was first described by Nedergaard and her colleagues in 2012. They showed how cerebral spinal fluid (CSF) is pumped into brain tissue and flushes away waste, including the proteins beta amyloid and tau that are associated with Alzheimer's disease and other forms of dementia.
Subsequent research has shown that the glymphatic system is more active while we sleep, can be damaged by stroke and trauma, and improves with exercise.
Science Daily reported that the new study was conducted on mice. It examined the impact of both acute and chronic alcohol exposure. When they studied the brains of animals exposed to high levels of alcohol over a long period of time, the researchers observed high levels of a molecular marker for inflammation, particularly in cells called astrocytes which are key regulators of the glymphatic system. They also noted impairment of the animal's cognitive abilities and motor skills.
Animals with low levels of alcohol consumption, analogous to approximately 2 ½ drinks per day, showed less inflammation in the brain and their glymphatic system was more efficient in moving CSF through the brain and removing waste, compared to control mice who were not exposed to alcohol, the website reported.
Get latest news & live updates on the go on your pc with News App. Download The Times of India news app for your device. Read more Home news in English and other languages.
Rosamma Thomas| TNN | Feb 6, 2018, 20:20 IST
62
JAIPUR: Have you found your teetotaler friends a bit boring? Now here's scientific evidence to show that a little alcohol is just the best thing for the brain. A new study in the journal Scientific Reports shows that low levels of alcohol consumption tamp down inflammation and helps the brain clear away toxins, including those associated with Alzheimer's disease.
Website Science Daily quoted Maiken Nedergaard, lead author of this study and co-director of the Center for Translational Neuromedicine at the University of Rochester Medical Center (URMC) as saying: "Prolonged intake of excessive amounts of ethanol is known to have adverse effects on the central nervous system. However, in this study we have shown for the first time that low doses of alcohol are potentially beneficial to brain health, namely it improves the brain's ability to remove waste."
Excessive alcohol consumption is shown to be addictive and a health hazard. In many parts of rural Rajasthan, for instance, women have been campaigning for shuttering the local liquor vend. However, studies have shown now that lower levels of drinking lead to reduced risk of cardiovascular diseases and a number of cancers.
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Nedergaard's research focuses on the glymphatic system, the brain's unique cleaning process that was first described by Nedergaard and her colleagues in 2012. They showed how cerebral spinal fluid (CSF) is pumped into brain tissue and flushes away waste, including the proteins beta amyloid and tau that are associated with Alzheimer's disease and other forms of dementia.
Subsequent research has shown that the glymphatic system is more active while we sleep, can be damaged by stroke and trauma, and improves with exercise.
Science Daily reported that the new study was conducted on mice. It examined the impact of both acute and chronic alcohol exposure. When they studied the brains of animals exposed to high levels of alcohol over a long period of time, the researchers observed high levels of a molecular marker for inflammation, particularly in cells called astrocytes which are key regulators of the glymphatic system. They also noted impairment of the animal's cognitive abilities and motor skills.
Animals with low levels of alcohol consumption, analogous to approximately 2 ½ drinks per day, showed less inflammation in the brain and their glymphatic system was more efficient in moving CSF through the brain and removing waste, compared to control mice who were not exposed to alcohol, the website reported.
Get latest news & live updates on the go on your pc with News App. Download The Times of India news app for your device. Read more Home news in English and other languages.