Shabz Nist
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Sequencing of a Malayali genome reveals similarities with Caucasians
At a recent conference on Next Generation Sequencing at Thiruvananthapuram, it was revealed that preliminary analysis (unpublished data) of the Malayali genome shows great similarity with Caucasian genome (white race) as against Chinese or African genomes. Additionally, several novel variations in the genome have been identified which may help in understanding predisposition to certain diseases.
The sequencing effort was led by Dr. Ravi Gupta and his team at the Kochi-based SciGenomics Labs in close collaboration with Dr. Stephan Suschters laboratory at Pennsylvania State University, USA.
Since first human genome was sequenced in 2001, we are trying to understand how humans have evolved and what makes us different from other species. Such studies show how different races might be closer rather than otherwise thought.
Moreover, the use of genomic information is important for developing drugs targeted for specific genetic disorders or rare diseases. Even though the gap between basic research and clinical applications based on genome sequencing is still huge due to complexity of the biological interactions which goes beyond simple DNA base pairing, it is undoubtedly the first crucial step towards better understanding of evolution as well as beginning of personalized medicine for human kind.
Sequencing of a Malayali genome reveals similarities with Caucasians | indiabioscience.org
At a recent conference on Next Generation Sequencing at Thiruvananthapuram, it was revealed that preliminary analysis (unpublished data) of the Malayali genome shows great similarity with Caucasian genome (white race) as against Chinese or African genomes. Additionally, several novel variations in the genome have been identified which may help in understanding predisposition to certain diseases.
The sequencing effort was led by Dr. Ravi Gupta and his team at the Kochi-based SciGenomics Labs in close collaboration with Dr. Stephan Suschters laboratory at Pennsylvania State University, USA.
Since first human genome was sequenced in 2001, we are trying to understand how humans have evolved and what makes us different from other species. Such studies show how different races might be closer rather than otherwise thought.
Moreover, the use of genomic information is important for developing drugs targeted for specific genetic disorders or rare diseases. Even though the gap between basic research and clinical applications based on genome sequencing is still huge due to complexity of the biological interactions which goes beyond simple DNA base pairing, it is undoubtedly the first crucial step towards better understanding of evolution as well as beginning of personalized medicine for human kind.
Sequencing of a Malayali genome reveals similarities with Caucasians | indiabioscience.org